Characterization of SGLT-2 Inhibitor Users in the Patient-Centered Clinical Research Network (PCORnet)

The objective of this request was to assess the feasibility of using national Patient-Centered Clinical Research Network (PCORnet) data to complement results from queries run against the Sentinel Distributed Database (SDD). PCORnet is comprised of electronic health record data. This request aims to describe the demographic, vital, and clinical characteristics of patients receiving a prescription for sodium-glucose cotransporter-2 (SGLT-2) inhibitors and other select anti-diabetic medications.

We used a retrospective study design to identify prevalent users of SGLT-2 inhibitors or sitagliptin within the PCORnet network between March 1, 2013, and June 30, 2018. We included data from 25 PCORnet Data Marts in this report. We distributed this request on October 2, 2019.