Utilization Patterns of Qsymia (Phentermine/Topiramate)

Project Title Utilization Patterns of Qsymia (Phentermine/Topiramate)
Date Posted
Wednesday, August 7, 2019
Project ID
cder_mpl1r_wp059, cder_mpl1r_wp060
Status
Complete
Deliverables
Description

The goal of this request was to estimate the number of incident users of Qsymia (combination product of phentermine and topiramate), phentermine, topiramate, and concomitant phentermine and topiramate in the Sentinel Distributed Database (SDD). Data from September 17, 2012 to April 30, 2017 from 16 Data Partners contributing to the SDD were included in these reports. This request was distributed on August 17, 2017.

Report 1 characterizes the uptake and utilization of Qsymia, phentermine, and topiramate, including the distribution of days supply, length of treatment episodes, and time to drug initiation.

Report 2 estimates the number of incident users of these drugs along with concomitant phentermine and topiramate, with additional estimates among individuals with a history of either epilepsy or seizures, with a history of migraines, and with no history of those conditions. 

Medical Product
Qsymia
phentermine HCl
phentermine/topiramate
topiramate
Population / Cohort
Individuals 18 years of age or older
Time Period
September 17, 2012 - April 30, 2017
Assessment Type
Exploratory Analyses
Study Type
Modular Program
Data Sources
Sentinel Distributed Database (SDD)
FDA Center
CDER