Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Clostridium difficile Events After Use of Oral Clindamycin versus Penicillins

Project Title Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Clostridium difficile Events After Use of Oral Clindamycin versus Penicillins
Date Posted
Tuesday, March 27, 2018
Status
Complete
Deliverables
Description

This statistical methods project is one of four workgroups that used exposure/outcome pairs with known positive associations to test Mini-Sentinel (now Sentinel) routine querying tools. Specifically, these known positive associations tested the Cohort Identification and Descriptive Analysis (CIDA) tool in combination with the Propensity Score Analysis (PSA) tool.

This known positive test case assessed oral clindamycin versus penicillins and risk of clostridium difficile infection. Data from January 1, 2006 to December 31, 2013 from 10 health plans contributing to the Mini-Sentinel Distributed Database (MSDD) were included in this report. This request was distributed on April 2, 2015.

Project ID
to16_cap_mpl2r_wp002_nsdp_v03
Medical Product
clindamycin
Health Outcome
clostridium difficile
Population / Cohort
All individuals
Time Period
January 1, 2006 - December 31, 2013
Data Sources
Mini-Sentinel Distributed Database (MSDD)
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