Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Gastrointestinal (GI) Bleeding Following New Use of Warfarin Compared with Statins

Project Title Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Gastrointestinal (GI) Bleeding Following New Use of Warfarin Compared with Statins
Date Posted
Friday, February 23, 2018
Status
Complete
Deliverables
Description

This statistical methods project is one of four workgroups that used exposure/outcome pairs with known positive associations to test Mini-Sentinel (now Sentinel) routine querying tools. Specifically, these known positive associations tested the Cohort Identification and Descriptive Analysis (CIDA) tool in combination with the Propensity Score Analysis (PSA) tool.

This known positive test case assessed the association between new use of warfarin and gastrointestinal (GI) bleeding, with statins as the comparison exposure. Data from January 1, 2012 to September 30, 2015 from 14 Data Partners contributing to the Sentinel Distributed Database (SDD) were included in this report. 

Project ID
to16_cap_mpl2r_wp008_nsdp_v02
Medical Product
statin
warfarin
Health Outcome
gastrointestinal hemorrhage
Population / Cohort
Individuals 18 years of age or older
Time Period
January 1, 2012 - September 30, 2015
Data Sources
Sentinel Distributed Database (SDD)
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