Sentinel Innovation Center (IC)

The IC is a test bed to identify, develop, and evaluate innovative methods. Their goal is to enhance Sentinel’s capabilities. These capabilities include:

  • New analysis tools 
  • Novel data sources 
  • State-of-the-art approaches to automate key epidemiologic study operations

Future Plans of the Innovation Center

The IC is developing a scientific blueprint for the next five years. The blueprint will address initiatives around:

  • Signal identification
  • Use of advanced analytics
  • Real-world evidence capabilities

The IC is exploring novel ways to extract and structure electronic health records.

structure of the Innovation Center

Lead Hubs

The IC has four Lead Hubs. These four hubs make up the Executive Leadership Team. Below are the four Lead Hubs in the Executive Leadership Team.

  1. Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School
  2. Duke Clinical Research Institute
  3. Vanderbilt University Medical Center Department of Biomedical Informatics
  4. Kaiser Permanente Washington Health Research Institute & University of Washington School of Public Health

Innovation Center Advisory Committee

The Advisory Committee supports the Lead Hubs. The Advisory Committee provides strategic guidance to the IC. It comprises top thought leaders in healthcare innovation. This includes academia, government, and industry.

Innovation Cores

The IC has developed four new Innovation Cores around:

  • Advanced Analytics
  • Novel Data Sources
  • Informatics
  • Randomized Trial and Real-World Evidence (RWE) innovation

The Innovation Cores identify novel technologies that could lead to new innovation projects.

Innovation Partners and the National Network of Innovation Experts

Innovation Partners are industry leaders in technology innovation.

The National Network of Innovation Experts also works with the Innovation Cores. It comprises individuals in academic and other research settings.  They have expertise in various domains of methods, innovation, and technology.

Together, these two groups lead and support projects within the IC. They are innovators and pioneers in:

  • Data science
  • Pharmacoepidemiology
  • Biostatistics
  • Biomedical informatics
  • Natural language processing
  • Machine learning and other areas of artificial intelligence
  • Signal detection
  • Advanced causal inference methods
  • Data linkage and integration
  • Pragmatic trials
  • Real-world evidence generation

Below is a list of Advisory Committee members, Innovation Partners, and National Network of Innovation Experts.

  • Aetion
  • Amazon
  • American Medical Informatics Association
  • Boston Children’s Hospital
  • Columbia University
  • Concerto HealthAI
  • Corrona
  • doc.ai
  • Duke Margolis Center for Health Policy
  • Duke University
  • Epic
  • Evidation
  • General Dynamics Information Technology (GDIT)
  • Harvard School of Public Health
  • HCA Healthcare
  • Healthagen (Aetna)
  • HealthCore
  • HealthPartners Institute
  • Health Sciences South Carolina
  • Humana
  • Kaiser Permanente Colorado Institute for Health Research
  • Kaiser Permanente Hawaii
  • Kaiser Permanente Mid-Atlantic
  • Kaiser Permanente Northern California
  • Kaiser Permanente Northwest
  • Marshfield Clinic
  • Massachusetts General Hospital
  • MDxHealth
  • Medical University of South Carolina
  • Microsoft Healthcare NExT
  • Microsoft Research
  • Northeastern University
  • Oak Ridge National Laboratory
  • Observational Health Data Sciences and Informatics (OHDSI)
  • Optum Labs
  • Optum Life Sciences
  • Partners HealthCare System
  • PatientsLikeMe
  • Penn State University
  • Putnam Data Sciences
  • PRACnet (Humana)
  • Rutgers University
  • Stanford University
  • STAR Clinical Research Network
  • TriNetX
  • University of Alabama
  • University of California, Berkeley
  • University of Illinois
  • University of Iowa
  • University of Florida
  • University of Michigan
  • University of Pennsylvania
  • University of Pittsburgh School of Medicine
  • University of Tennessee
  • University of Utah
  • Veradigm
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