Health Outcomes of Interest | Sentinel Initiative

This webpage provides access to Sentinel Health Outcome of Interest (HOI) activities that have been conducted by the FDA. The search below can be used to find more information about each study type or health outcome. Code lists (such as ICD-9-CM codes, ICD-10 codes, procedure codes, etc.), algorithm criteria, and literature reviews for these activities appear in the form of reports or Microsoft Excel workbooks.

Study Types

Novel Approaches to More Efficient Outcome Validation

Aim to identify solutions to the governance, process, and technology barriers to support more efficient outcome validation as a starting point for greater sufficiency of Active Risk Identification and Analysis (ARIA), a stronger Sentinel System, and a more rigorous evidence generation enterprise.

Validations Supported by Traditional Medical Chart Review

Involve checking codes derived from electronic medical records and administrative claims-based data against medical chart information to verify that the electronic codes validly and reliably identify individuals with particular medical conditions.

Outcomes Assessed in Descriptive and Inferential Analyses

Identify medical conditions defined as outcomes of interest in descriptive and inferential analyses and their respective code lists and algorithm criteria.

Coding Trend Analyses

Display the trends for outcome definitions across the ICD-9-CM and ICD-10-CM/PCS eras.

Literature Reviews

Primarily concern identification of health outcomes and focus on determining which codes in electronic medical record and administrative claims-based data are the most valid and reliable indicators of the presence of particular medical conditions.

Search Health Outcomes of Interest

Title	HOI Study Type	Outcomes	Date
Thromboembolic Stroke Algorithm Defined in "Thromboembolic Stroke, Intracranial Hemorrhage, Gastrointestinal Bleeding, and Major Extracranial Bleeding Following Apixaban, Dabigatran, and Rivaroxaban Use in Patients Aged 64 Years and Younger with Atrial Fibrillation: An Inverse Probability of Treatment Weighting Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	thromboembolic stroke View More Outcomes (1)	08/21/2024
Major Extracranial Bleeding Algorithm Defined in "Thromboembolic Stroke, Intracranial Hemorrhage, Gastrointestinal Bleeding, and Major Extracranial Bleeding Following Apixaban, Dabigatran, and Rivaroxaban Use in Patients Aged 64 Years and Younger with Atrial Fibrillation: An Inverse Probability of Treatment Weighting Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	major extracranial bleeding View More Outcomes (1)	08/21/2024
Intracranial Hemorrhage Algorithm Defined in "Thromboembolic Stroke, Intracranial Hemorrhage, Gastrointestinal Bleeding, and Major Extracranial Bleeding Following Apixaban, Dabigatran, and Rivaroxaban Use in Patients Aged 64 Years and Younger with Atrial Fibrillation: An Inverse Probability of Treatment Weighting Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intracranial hemorrhage View More Outcomes (1)	08/21/2024
Gastrointestinal Bleeding Algorithm Defined in "Thromboembolic Stroke, Intracranial Hemorrhage, Gastrointestinal Bleeding, and Major Extracranial Bleeding Following Apixaban, Dabigatran, and Rivaroxaban Use in Patients Aged 64 Years and Younger with Atrial Fibrillation: An Inverse Probability of Treatment Weighting Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	gastrointestinal bleeding View More Outcomes (1)	08/21/2024
COVID-19 Severity Algorithm Defined in "Risk of Adverse Maternal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	COVID-19 severity View More Outcomes (1)	08/07/2024
Preterm Birth Algorithm Defined in "Risk of Adverse Maternal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	preterm birth View More Outcomes (1)	08/07/2024
Caesarean Section Algorithm Defined in "Risk of Adverse Maternal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	caesarean section View More Outcomes (1)	08/07/2024
Maternal Death Algorithm Defined in "Risk of Adverse Maternal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	maternal death View More Outcomes (1)	08/07/2024
Gestational Diabetes Mellitus Algorithm Defined in "Risk of Adverse Maternal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	gestational diabetes mellitus View More Outcomes (1)	08/07/2024
Major Congenital Malformation Algorithm Defined in "Risk of Adverse Neonatal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	major congenital malformation View More Outcomes (1)	08/02/2024
Low Birth Weight Algorithm Defined in "Risk of Adverse Neonatal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	low birth weight View More Outcomes (1)	08/02/2024
Small for Gestational Age Algorithm Defined in "Risk of Adverse Neonatal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	small for gestational age View More Outcomes (1)	08/02/2024
COVID-19 Severity Algorithm Defined in "Risk of Adverse Neonatal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	COVID-19 severity View More Outcomes (1)	08/02/2024
Microcephaly Algorithm Defined in "Risk of Adverse Neonatal Health Outcomes Among Pregnant Patients With and Without COVID-19: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	microcephaly View More Outcomes (1)	08/02/2024
Intentional Self-Harm Algorithm Defined in "Intentional Self-Harm Following Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA) Use in Patients with Diabetes: An Inverse Probability of Treatment Weighting Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intentional self-harm View More Outcomes (1)	07/22/2024
Serious Infection Algorithm Defined in "Serious Infection Following Ustekinumab Use in Patients with Crohn’s Disease: An Inverse Probability of Treatment Weighting Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	serious infection View More Outcomes (1)	06/24/2024
Interstitial Lung Disease Algorithm Defined in "Interstitial Lung Disease (ILD) Rates in Patients with Inflammatory Bowel Disease (IBD) and Following IBD Advanced Therapy: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	interstitial lung disease View More Outcomes (1)	05/09/2024
Interstitial Lung Disease Algorithm Defined in "Interstitial Lung Disease (ILD) in Patients with Inflammatory Bowel Disease (IBD) and Following Vedolizumab or Natalizumab Initiation: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	interstitial lung disease View More Outcomes (1)	05/09/2024
Intentional Self-Harm Algorithm Defined in "Intentional Self-Harm Following Montelukast Use in Patients with Asthma: An Updated Analysis Using ICD-10-CM Coding" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intentional self-harm View More Outcomes (1)	03/21/2024
Coding Trend Analyses: Ulcerative Colitis Coding Trend Analyses	Coding Trend Analyses	ulcerative colitis View More Outcomes (1)	02/08/2024
Coding Trend Analyses: Endoscopy Coding Trend Analyses	Coding Trend Analyses	endoscopy View More Outcomes (1)	02/08/2024
Coding Trend Analyses: Diverticulitis and Colitis Coding Trend Analyses	Coding Trend Analyses	colitis , diverticulitis View More Outcomes (2)	02/08/2024
Coding Trend Analyses: Colectomy, Colostomy, and Ileostomy Coding Trend Analyses	Coding Trend Analyses	colectomy , colostomy , ileostomy View More Outcomes (3)	02/08/2024
Coding Trend Analyses: Crohn's Disease Coding Trend Analyses	Coding Trend Analyses	Crohn's disease View More Outcomes (1)	02/08/2024
Coding Trend Analyses: Biopsy Coding Trend Analyses	Coding Trend Analyses	biopsy View More Outcomes (1)	02/08/2024
COVID-19 Chart Validation of COVID-19 Severity Algorithm Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	COVID-19 View More Outcomes (1)	01/19/2024
Non-Cardiac Congenital Malformations Algorithm Defined in "Risk of Non-Cardiac Congenital Malformations Following Armodafinil or Modafinil Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	non-cardiac congenital malformations View More Outcomes (1)	11/13/2023
Severe COVID-19 Algorithm Defined in COVID-19 Hospitalization and Severe COVID-19 Infection Following Proton Pump Inhibitor (PPI) Use in Patients with Gastroesophageal Reflux Disease (GERD): An Inverse Probability of Treatment Weighting Analysis Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	Severe COVID-19 View More Outcomes (1)	10/10/2023
COVID-19 Hospitalization Algorithm Defined in COVID-19 Hospitalization and Severe COVID-19 Infection Following Proton Pump Inhibitor (PPI) Use in Patients with Gastroesophageal Reflux Disease (GERD): An Inverse Probability of Treatment Weighting Analysis Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	COVID-19 hospitalization View More Outcomes (1)	10/10/2023
Angioedema Algorithm Defined in "Angioedema Following Sacubitril/Valsartan Use in Patients with Heart Failure: An Updated Propensity Score Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	angioedema View More Outcomes (1)	04/21/2023
COVID-19 Diagnosis Algorithm Defined in "Racial Differences in COVID-19 Outcomes (2020-2021)" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	COVID-19 Diagnosis View More Outcomes (1)	04/06/2023
Critical COVID-19 Algorithm Defined in "Racial Differences in COVID-19 Outcomes (2020-2021)" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	Critical COVID-19 View More Outcomes (1)	04/06/2023
Congenital Cardiac Malformation Algorithm Defined in "Congenital Malformations Observed in the Mother’s Records Following Fingolimod Use During Pregnancy: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	congenital cardiac malformations View More Outcomes (1)	03/03/2023
Congenital Cardiac Malformation Algorithm Defined in "Congenital Malformations Observed in the Mother’s or Linked Infant’s Records Following Fingolimod Use During Pregnancy: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	congenital cardiac malformations View More Outcomes (1)	03/03/2023
Congenital Non-Cardiac/Non-Urinary Malformation Algorithm Defined in "Congenital Malformations Observed in the Mother’s Records Following Fingolimod Use During Pregnancy: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	congenital non-cardiac/non-urinary malformations View More Outcomes (1)	03/03/2023
Congenital Non-Cardiac/Non-Urinary Malformation Algorithm Defined in "Congenital Malformations Observed in the Mother’s or Linked Infant’s Records Following Fingolimod Use During Pregnancy: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	congenital non-cardiac/non-urinary malformations View More Outcomes (1)	03/03/2023
Congenital Urinary Malformation Algorithm Defined in "Congenital Malformations Observed in the Mother’s Records Following Fingolimod Use During Pregnancy: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	congenital urinary malformations View More Outcomes (1)	03/03/2023
Congenital Urinary Malformation Algorithm Defined in "Congenital Malformations Observed in the Mother’s or Linked Infant’s Records Following Fingolimod Use During Pregnancy: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	congenital urinary malformations View More Outcomes (1)	03/03/2023
Valganciclovir Use in Children with Congenital Cytomegalovirus Infection: Chart Review Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	Congenital cytomegalovirus infection (cCMV) View More Outcomes (1)	02/09/2023
Atrioventricular Block Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	atrioventricular block View More Outcomes (1)	02/09/2023
Septal Myectomy Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	septal myectomy View More Outcomes (1)	02/09/2023
Atrioventricular Block Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: An Updated Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	atrioventricular block View More Outcomes (1)	02/09/2023
Septal Myectomy Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: An Updated Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	septal myectomy View More Outcomes (1)	02/09/2023
Permanent Pacemaker Placement Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	permanent pacemaker placement View More Outcomes (1)	02/09/2023
Heart Failure Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: An Updated Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	heart failure View More Outcomes (1)	02/09/2023
Permanent Pacemaker Placement Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: An Updated Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	permanent pacemaker placement View More Outcomes (1)	02/09/2023
Heart Failure Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	heart failure View More Outcomes (1)	02/09/2023
Ventricular Arrhythmia Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	ventricular arrhythmia View More Outcomes (1)	02/09/2023
Myocardial Infarction Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: An Updated Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	myocardial infarction View More Outcomes (1)	02/09/2023
Ventricular Arrhythmia Algorithm Defined in "Cardiovascular Outcomes Following Percutaneous Transluminal Septal Myocardial Ablation (PTSMA) Procedures: An Updated Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	ventricular arrhythmia View More Outcomes (1)	02/09/2023
Seizure Algorithm Defined in "Seizures Following Gadolinium-Based Contrast Agents Exposure: A Self-Controlled Risk Interval Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	seizure View More Outcomes (1)	06/29/2022
Intracranial Hemorrhage Algorithm Defined in "Thromboembolic Stroke, Major Extracranial Bleeding, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Direct Oral Anticoagulant Use in Patients Aged 65 and Older: An IPTW Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intracranial hemorrhage View More Outcomes (1)	01/06/2022
Major Extracranial Bleeding Algorithm Defined in "Thromboembolic Stroke, Major Extracranial Bleeding, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Direct Oral Anticoagulant Use in Patients Aged 65 and Older: An IPTW Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	major extracranial bleeding View More Outcomes (1)	01/06/2022
Gastrointestinal Bleeding Algorithm Defined in "Thromboembolic Stroke, Major Extracranial Bleeding, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Direct Oral Anticoagulant Use in Patients Aged 65 and Older: An IPTW Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	gastrointestinal bleeding View More Outcomes (1)	01/06/2022
Thromboembolic Stroke Algorithm Defined in "Thromboembolic Stroke, Major Extracranial Bleeding, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Direct Oral Anticoagulant Use in Patients Aged 65 and Older: An IPTW Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	thromboembolic stroke View More Outcomes (1)	01/06/2022
Hospitalized Depression Algorithm Defined in "Intentional Self-Harm and Hospitalized Depression Following Sertraline Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	hospitalized depression View More Outcomes (1)	12/14/2021
Intentional Self-Harm Algorithm Defined in "Intentional Self-Harm and Hospitalized Depression Following Sertraline Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intentional self-harm View More Outcomes (1)	12/14/2021
Angioedema and Serious Angioedema Algorithms Defined in "Angioedema following Sacubitril/Valsartan Use in Patients with Heart Failure: A Propensity Score Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	angioedema View More Outcomes (1)	04/21/2021
Cutaneous Small-Vessel Vasculitis Algorithm Defined in "Cutaneous Small-Vessel Vasculitis following Dabigatran, Rivaroxaban, and Apixaban Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	cutaneous small-vessel vasculitis View More Outcomes (1)	11/02/2020
Intracranial Hemorrhage Algorithm Defined in "Thromboembolic Stroke, Intracranial Hemorrhage, Gastrointestinal Bleeding, and Major Extracranial Bleeding following Dabigatran, Rivaroxaban, and Apixaban Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intracranial hemorrhage View More Outcomes (1)	10/30/2020
Major Extracranial Bleeding Algorithm Defined in "Thromboembolic Stroke, Intracranial Hemorrhage, Gastrointestinal Bleeding, and Major Extracranial Bleeding following Dabigatran, Rivaroxaban, and Apixaban Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	major extracranial bleeding View More Outcomes (1)	10/30/2020
Thromboembolic Stroke Algorithm Defined in "Thromboembolic Stroke, Intracranial Hemorrhage, Gastrointestinal Bleeding, and Major Extracranial Bleeding following Dabigatran, Rivaroxaban, and Apixaban Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	thromboembolic stroke View More Outcomes (1)	10/30/2020
Gastrointestinal Bleeding Algorithm Defined in "Thromboembolic Stroke, Intracranial Hemorrhage, Gastrointestinal Bleeding, and Major Extracranial Bleeding following Dabigatran, Rivaroxaban, and Apixaban Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	gastrointestinal bleeding View More Outcomes (1)	10/30/2020
Oral Clefts Algorithm Defined in "A New Propensity Score Matched Analysis Tool for Pregnancy: Replicating A Study of Oral Clefts following Topiramate Use during the First Trimester of Pregnancy" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	oral clefts View More Outcomes (1)	10/29/2020
Major Extracranial Bleeding Algorithm Defined in "Stroke, Intracranial Hemorrhage, and Bleeding following Dabigatran, Rivaroxaban, and Apixaban Use in Patients Aged 65 or Older: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	major extracranial bleeding View More Outcomes (1)	09/16/2020
Intracranial Hemorrhage Algorithm Defined in "Stroke, Intracranial Hemorrhage, and Bleeding following Dabigatran, Rivaroxaban, and Apixaban Use in Patients Aged 65 or Older: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intracranial hemorrhage View More Outcomes (1)	09/16/2020
Thromboembolic Stroke Algorithm Defined in "Stroke, Intracranial Hemorrhage, and Bleeding following Dabigatran, Rivaroxaban, and Apixaban Use in Patients Aged 65 or Older: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	thromboembolic stroke View More Outcomes (1)	09/16/2020
Gastrointestinal Bleeding Algorithm Defined in "Stroke, Intracranial Hemorrhage, and Bleeding following Dabigatran, Rivaroxaban, and Apixaban Use in Patients Aged 65 or Older: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	gastrointestinal bleeding View More Outcomes (1)	09/16/2020
Cataracts Algorithm Defined in "Glaucoma, Cataracts, Diminished Visual Acuity, and Nasal Septal Perforation following Mometasone Sinus Implant Use in Patients with Nasal Polyposis: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	cataracts View More Outcomes (1)	08/05/2020
Nasal Septal Perforation Algorithm Defined in "Glaucoma, Cataracts, Diminished Visual Acuity, and Nasal Septal Perforation following Mometasone Sinus Implant Use in Patients with Nasal Polyposis: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	nasal septal perforation View More Outcomes (1)	08/05/2020
Glaucoma Algorithm Defined in "Glaucoma, Cataracts, Diminished Visual Acuity, and Nasal Septal Perforation following Mometasone Sinus Implant Use in Patients with Nasal Polyposis: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	glaucoma View More Outcomes (1)	08/05/2020
Diminished Visual Acuity Algorithm Defined in "Glaucoma, Cataracts, Diminished Visual Acuity, and Nasal Septal Perforation following Mometasone Sinus Implant Use in Patients with Nasal Polyposis: A Descriptive Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	diminished visual acuity View More Outcomes (1)	08/05/2020
Cardiac Congenital Malformations Algorithm Defined in "Risk of Cardiac Congenital Malformations Following Armodafinil or Modafinil Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	cardiac congenital malformations View More Outcomes (1)	07/30/2020
Hysterectomy Algorithm Defined in "Gynecologic Surgery following Permanent Sterilization: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	hysterectomy View More Outcomes (1)	07/23/2020
Salpingectomy Algorithm Defined in "Gynecologic Surgery following Permanent Sterilization: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	salpingectomy View More Outcomes (1)	07/23/2020
Coding Trend Analyses: Epilepsy - Inpatient Care Setting Coding Trend Analyses	Coding Trend Analyses	epilepsy View More Outcomes (1)	06/03/2020
Coding Trend Analyses: Alzheimer's Disease Coding Trend Analyses	Coding Trend Analyses	Alzheimer's disease View More Outcomes (1)	06/03/2020
Validation of Stillbirth in ICD-10-CM Post-Hoc Analyses Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	stillbirth View More Outcomes (1)	06/03/2020
Coding Trend Analyses: Epilepsy - Emergency Department Care Setting Coding Trend Analyses	Coding Trend Analyses	epilepsy View More Outcomes (1)	06/03/2020
Coding Trend Analyses: Diabetes Coding Trend Analyses	Coding Trend Analyses	diabetes View More Outcomes (1)	01/28/2020
Coding Trend Analyses: Acute Myocardial Infarction Coding Trend Analyses	Coding Trend Analyses	acute myocardial infarction (AMI) View More Outcomes (1)	01/28/2020
Coding Trend Analyses: Angioedema Coding Trend Analyses	Coding Trend Analyses	angioedema View More Outcomes (1)	01/28/2020
Coding Trend Analyses: Hypertension Coding Trend Analyses	Coding Trend Analyses	hypertension View More Outcomes (1)	01/22/2020
Coding Trend Analyses: Hodgkin's Lymphoma Coding Trend Analyses	Coding Trend Analyses	Hodgkin's lymphoma View More Outcomes (1)	12/09/2019
Coding Trend Analyses: Macrophage Activation Syndrome Coding Trend Analyses	Coding Trend Analyses	macrophage activation syndrome View More Outcomes (1)	11/26/2019
Coding Trend Analyses: Pulmonary Arterial Hypertension Coding Trend Analyses	Coding Trend Analyses	pulmonary arterial hypertension View More Outcomes (1)	11/26/2019
Coding Trend Analyses: Adult-Onset Still's Disease Coding Trend Analyses	Coding Trend Analyses	adult-onset Still's disease View More Outcomes (1)	11/26/2019
Coding Trend Analyses: Alveolar Proteinosis Coding Trend Analyses	Coding Trend Analyses	alveolar proteinosis View More Outcomes (1)	11/26/2019
Coding Trend Analyses: Systemic Juvenile Idiopathic Arthritis Coding Trend Analyses	Coding Trend Analyses	systemic juvenile idiopathic arthritis View More Outcomes (1)	11/26/2019
Coding Trend Analyses: Interstitial Lung Disease Coding Trend Analyses	Coding Trend Analyses	interstitial lung disease View More Outcomes (1)	11/26/2019
Coding Trend Analyses: Non-Hodgkin's Lymphoma Coding Trend Analyses	Coding Trend Analyses	non-Hodgkin's lymphoma View More Outcomes (1)	11/26/2019
Coding Trend Analyses: Acute Pancreatitis Coding Trend Analyses	Coding Trend Analyses	acute pancreatitis View More Outcomes (1)	11/01/2019
Coding Trend Analyses: Serious Infections Coding Trend Analyses	Coding Trend Analyses	serious infection View More Outcomes (1)	11/01/2019
Coding Trend Analyses: Anaphylaxis Coding Trend Analyses	Coding Trend Analyses	anaphylaxis View More Outcomes (1)	10/30/2019
Coding Trend Analyses: Gastrointestinal Bleed Coding Trend Analyses	Coding Trend Analyses	gastrointestinal (GI) bleed View More Outcomes (1)	10/11/2019
Coding Trend Analyses: Hospitalized Influenza Coding Trend Analyses	Coding Trend Analyses	hospitalized influenza View More Outcomes (1)	10/11/2019
Coding Trend Analyses: Poisoning Coding Trend Analyses	Coding Trend Analyses	poisoning View More Outcomes (1)	09/27/2019
Coding Trend Analyses: Brain Tumor Coding Trend Analyses	Coding Trend Analyses	brain tumor View More Outcomes (1)	09/27/2019
Coding Trend Analyses: Head Injury Coding Trend Analyses	Coding Trend Analyses	head injury View More Outcomes (1)	09/27/2019
Coding Trend Analyses: Kidney Disease Coding Trend Analyses	Coding Trend Analyses	kidney disease View More Outcomes (1)	09/27/2019
Coding Trend Analyses: Syncope Coding Trend Analyses	Coding Trend Analyses	syncope View More Outcomes (1)	09/27/2019
Transfusion-Related Acute Lung Injury After Red Blood Cell, Plasma, and Platelet Administration 2013-2015 Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	transfusion-related acute lung injury (TRALI) View More Outcomes (1)	09/09/2019
Coding Trend Analyses: Dialysis Coding Trend Analyses	Coding Trend Analyses	dialysis View More Outcomes (1)	09/06/2019
Coding Trend Analyses: Kidney Replacement Coding Trend Analyses	Coding Trend Analyses	kidney replacement View More Outcomes (1)	09/04/2019
Coding Trend Analyses: Stillbirth - Outpatient Care Setting Coding Trend Analyses	Coding Trend Analyses	stillbirth View More Outcomes (1)	08/30/2019
Coding Trend Analyses: Joint Replacement Coding Trend Analyses	Coding Trend Analyses	joint replacement View More Outcomes (1)	08/29/2019
Coding Trend Analyses: Valve Replacement Coding Trend Analyses	Coding Trend Analyses	valve replacement View More Outcomes (1)	08/27/2019
Coding Trend Analyses: Stillbirth - Inpatient Care Setting Coding Trend Analyses	Coding Trend Analyses	stillbirth View More Outcomes (1)	08/27/2019
Coding Trend Analyses: Pulmonary Embolism Coding Trend Analyses	Coding Trend Analyses	pulmonary embolism View More Outcomes (1)	08/26/2019
Coding Trend Analyses: Mitral Stenosis Coding Trend Analyses	Coding Trend Analyses	mitral stenosis View More Outcomes (1)	08/26/2019
Coding Trend Analyses: Ischemic Stroke Coding Trend Analyses	Coding Trend Analyses	ischemic stroke View More Outcomes (1)	08/26/2019
Coding Trend Analyses: Intracranial Hemorrhage Coding Trend Analyses	Coding Trend Analyses	intracranial hemorrhage View More Outcomes (1)	08/26/2019
Coding Trend Analyses: Gastrointestinal Hemorrhage Coding Trend Analyses	Coding Trend Analyses	gastrointestinal hemorrhage View More Outcomes (1)	08/22/2019
Coding Trend Analyses: Deep Vein Thrombosis Coding Trend Analyses	Coding Trend Analyses	deep vein thrombosis View More Outcomes (1)	08/21/2019
Outpatient Depressive Disorder Algorithm Defined in "Neuropsychiatric Events following Montelukast Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	outpatient depressive disorder View More Outcomes (1)	08/19/2019
Inpatient Depressive Disorder Algorithm Defined in "Neuropsychiatric Events following Montelukast Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	inpatient depressive disorder View More Outcomes (1)	08/19/2019
Suicide Algorithm Defined in "Neuropsychiatric Events following Montelukast Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	suicide View More Outcomes (1)	08/19/2019
Self-Harm Algorithms Defined in "Neuropsychiatric Events following Montelukast Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	self-harm View More Outcomes (1)	08/19/2019
Coding Trend Analyses: Atrial Fibrillation Coding Trend Analyses	Coding Trend Analyses	atrial fibrillation View More Outcomes (1)	08/09/2019
Coding Trend Analyses: Non-Thyroid Endocrine Cancers Coding Trend Analyses	Coding Trend Analyses	non-thyroid endocrine cancer View More Outcomes (1)	07/12/2019
Coding Trend Analyses: Convulsions - Inpatient Care Setting Coding Trend Analyses	Coding Trend Analyses	convulsion View More Outcomes (1)	07/10/2019
Coding Trend Analyses: Convulsions - Emergency Department Care Setting Coding Trend Analyses	Coding Trend Analyses	convulsion View More Outcomes (1)	07/10/2019
Hip Replacement Algorithm Defined in "Fractures following Leuprolide Acetate Use: A Multiple Factor Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	hip replacement View More Outcomes (1)	07/02/2019
Fracture Algorithm Defined in "Fractures following Leuprolide Acetate Use: A Multiple Factor Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	fractures View More Outcomes (1)	07/02/2019
Major Fracture Algorithm Defined in "Fractures Following Leuprolide Acetate Use: A Multiple Factor Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	major fracture View More Outcomes (1)	07/02/2019
Temporomandibular Joint Replacement Algorithm Defined in "Fractures following Leuprolide Acetate Use: A Multiple Factor Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	temporomandibular joint replacement View More Outcomes (1)	07/02/2019
Squamous Cell Carcinoma Algorithm Defined in "Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	squamous cell carcinoma View More Outcomes (1)	06/11/2019
Basal Cell Carcinoma Algorithm Defined in "Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	basal cell carcinoma View More Outcomes (1)	06/11/2019
Development of a Chart Validation Table Novel Approaches to More Efficient Outcome Validation	Novel Approaches to More Efficient Outcome Validation		05/02/2019
Validation of Acute Pancreatitis Using Machine Learning and Multi-Site Adaptation for Anaphylaxis Novel Approaches to More Efficient Outcome Validation	Novel Approaches to More Efficient Outcome Validation	acute pancreatitis View More Outcomes (1)	04/30/2019
Coding Trend Analyses: Esophageal Cancer Coding Trend Analyses	Coding Trend Analyses	esophageal cancer View More Outcomes (1)	04/25/2019
Coding Trend Analyses: Kidney and Pelvis Cancer Coding Trend Analyses	Coding Trend Analyses	kidney and pelvis cancer View More Outcomes (1)	04/25/2019
Coding Trend Analyses: Lung Cancer Coding Trend Analyses	Coding Trend Analyses	lung cancer View More Outcomes (1)	04/25/2019
Coding Trend Analyses: Lymphoma Coding Trend Analyses	Coding Trend Analyses	lymphoma View More Outcomes (1)	04/25/2019
Coding Trend Analyses: Endometrial Cancer Coding Trend Analyses	Coding Trend Analyses	endometrial cancer View More Outcomes (1)	04/25/2019
Coding Trend Analysis: Leukemia Coding Trend Analyses	Coding Trend Analyses	leukemia View More Outcomes (1)	04/25/2019
Severe Uterine Bleed with Transfusion Management Algorithm Defined in "Severe Uterine Bleed following Novel Oral Anticoagulants Use: A Propensity Score Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	severe uterine bleed View More Outcomes (1)	04/18/2019
Severe Uterine Bleed with Surgical Management Algorithm Defined in "Severe Uterine Bleed following Novel Oral Anticoagulants Use: A Propensity Score Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	severe uterine bleed View More Outcomes (1)	04/18/2019
Coding Trend Analyses: Glaucoma Coding Trend Analyses	Coding Trend Analyses	glaucoma View More Outcomes (1)	04/16/2019
Coding Trend Analyses: Heart Failure Coding Trend Analyses	Coding Trend Analyses	heart failure View More Outcomes (1)	04/16/2019
Coding Trend Analyses: Cataracts Coding Trend Analyses	Coding Trend Analyses	cataracts View More Outcomes (1)	04/16/2019
Coding Trend Analyses: Nasal Septal Perforations Coding Trend Analyses	Coding Trend Analyses	nasal septal perforation View More Outcomes (1)	04/16/2019
Coding Trend Analyses: Nasal Polyps Coding Trend Analyses	Coding Trend Analyses	nasal polyps View More Outcomes (1)	04/16/2019
Coding Trend Analyses: Blindness Coding Trend Analyses	Coding Trend Analyses	blindness View More Outcomes (1)	04/15/2019
Coding Trend Analyses: Diabetes Mellitus with Pregnancy Coding Trend Analyses	Coding Trend Analyses	diabetes mellitus with pregnancy View More Outcomes (1)	04/15/2019
Coding Trend Analyses: Visual Acuity Coding Trend Analyses	Coding Trend Analyses	visual acuity View More Outcomes (1)	04/15/2019
Coding Trend Analyses: Urinary Bladder Cancer Coding Trend Analyses	Coding Trend Analyses	urinary bladder cancer View More Outcomes (1)	04/12/2019
Coding Trend Analyses: Pancreatic Cancer Coding Trend Analyses	Coding Trend Analyses	pancreatic cancer View More Outcomes (1)	04/12/2019
Coding Trend Analyses: Type 1 Diabetes Mellitus Coding Trend Analyses	Coding Trend Analyses	type 1 diabetes mellitus View More Outcomes (1)	04/09/2019
Coding Trend Analyses: Non-Melanoma Skin Cancer Coding Trend Analyses	Coding Trend Analyses	non-melanoma skin cancer View More Outcomes (1)	04/09/2019
Coding Trend Analyses: Diabetic Ketoacidosis Coding Trend Analyses	Coding Trend Analyses	diabetic ketoacidosis View More Outcomes (1)	04/09/2019
Coding Trend Analyses: Malignant Melanoma Cancer Coding Trend Analyses	Coding Trend Analyses	malignant melanoma cancer View More Outcomes (1)	04/09/2019
Coding Trend Analyses: Type 2 Diabetes Mellitus Coding Trend Analyses	Coding Trend Analyses	type 2 diabetes mellitus View More Outcomes (1)	04/09/2019
Coding Trend Analyses: Ischemic Heart Disease Coding Trend Analyses	Coding Trend Analyses	ischemic heart disease View More Outcomes (1)	04/05/2019
Coding Trend Analyses: Allergic Reactions Coding Trend Analyses	Coding Trend Analyses	allergic reaction View More Outcomes (1)	04/05/2019
Coding Trend Analyses: Anaphylaxis after Vaccination Coding Trend Analyses	Coding Trend Analyses	anaphylaxis View More Outcomes (1)	04/03/2019
Coding Trend Analyses: Bell's Palsy Coding Trend Analyses	Coding Trend Analyses	Bell’s palsy View More Outcomes (1)	04/03/2019
Coding Trend Analyses: Guillain-Barré Syndrome Coding Trend Analyses	Coding Trend Analyses	Guillain-Barré syndrome View More Outcomes (1)	04/03/2019
Coding Trend Analyses: Febrile Seizures Coding Trend Analyses	Coding Trend Analyses	febrile seizure View More Outcomes (1)	04/03/2019
Coding Trend Analyses: Prostate Cancer Coding Trend Analyses	Coding Trend Analyses	prostate cancer View More Outcomes (1)	04/03/2019
Acute Myocardial Infarction Algorithm Defined in "Acute Myocardial Infarction and Heart Failure following Saxagliptin or Sitagliptin Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	acute myocardial infarction (AMI) View More Outcomes (1)	04/01/2019
Heart Failure Algorithm Defined in "Acute Myocardial Infarction and Heart Failure Following Saxagliptin or Sitagliptin Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	heart failure View More Outcomes (1)	04/01/2019
Coding Trend Analyses: Thyroid Cancer Coding Trend Analyses	Coding Trend Analyses	thyroid cancer View More Outcomes (1)	03/29/2019
Coding Trend Analyses: Rectal Cancer Coding Trend Analyses	Coding Trend Analyses	rectal cancer View More Outcomes (1)	03/29/2019
Coding Trend Analyses: Gout Coding Trend Analyses	Coding Trend Analyses	gout View More Outcomes (1)	03/28/2019
Coding Trend Analyses: Anal Cancer Coding Trend Analyses	Coding Trend Analyses	anal cancer View More Outcomes (1)	03/28/2019
Coding Trend Analyses: Cervical Cancer Coding Trend Analyses	Coding Trend Analyses	cervical cancer View More Outcomes (1)	03/28/2019
Coding Trend Analyses: Female Breast Cancer Coding Trend Analyses	Coding Trend Analyses	female breast cancer View More Outcomes (1)	03/28/2019
Coding Trend Analyses: Colon Cancer Coding Trend Analyses	Coding Trend Analyses	colon cancer View More Outcomes (1)	03/28/2019
Coding Trend Analyses: Male Breast Cancer Coding Trend Analyses	Coding Trend Analyses	male breast cancer View More Outcomes (1)	03/28/2019
Coding Trend Analyses: Lower Limb Amputation Coding Trend Analyses	Coding Trend Analyses	lower limb amputation View More Outcomes (1)	03/01/2019
Coding Trend Analyses: Intracranial Hemorrhage - Inpatient Care Setting Coding Trend Analyses	Coding Trend Analyses	intracranial hemorrhage View More Outcomes (1)	03/01/2019
Coding Trend Analyses: Gestational Diabetes Mellitus Coding Trend Analyses	Coding Trend Analyses	gestational diabetes mellitus View More Outcomes (1)	03/01/2019
Coding Trend Analyses: Intracranial Hemorrhage - Any Care Setting Coding Trend Analyses	Coding Trend Analyses	intracranial hemorrhage View More Outcomes (1)	03/01/2019
Gastrointestinal Bleed Algorithm Defined in "Stroke, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Apixaban or Warfarin Use in Patients with Non-Valvular Atrial Fibrillation: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	gastrointestinal (GI) bleed View More Outcomes (1)	02/15/2019
Ischemic Stroke Algorithm Defined in "Stroke, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Apixaban or Warfarin Use in Patients with Non-Valvular Atrial Fibrillation: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	ischemic stroke View More Outcomes (1)	02/15/2019
Intracranial Hemorrhage Algorithm Defined in "Stroke, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Apixaban or Warfarin Use in Patients with Non-Valvular Atrial Fibrillation: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intracranial hemorrhage View More Outcomes (1)	02/15/2019
Influenza Vaccines and Birth Outcomes Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	cleft lip with cleft palate , cleft lip without cleft palate , cleft palate without cleft lip View More Outcomes (3)	02/06/2019
Machine Learning Pilot for Electronic Phenotyping of Health Outcomes of Interest Novel Approaches to More Efficient Outcome Validation	Novel Approaches to More Efficient Outcome Validation		11/13/2018
13-Valent Pneumococcal Conjugate Vaccination (PCV13) and Kawasaki Disease Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	Kawasaki disease View More Outcomes (1)	10/24/2018
Validation of Anaphylaxis Using Machine Learning Novel Approaches to More Efficient Outcome Validation	Novel Approaches to More Efficient Outcome Validation	anaphylaxis View More Outcomes (1)	10/11/2018
Validation of Stillbirth in ICD-10-CM Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	stillbirth View More Outcomes (1)	07/16/2018
Gastrointestinal Bleeding Algorithm Defined in "Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Gastrointestinal (GI) Bleeding Following New Use of Warfarin Compared with Statins" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	gastrointestinal (GI) bleed View More Outcomes (1)	06/25/2018
Coding Trend Analyses: Myocarditis Coding Trend Analyses	Coding Trend Analyses	myocarditis View More Outcomes (1)	06/15/2018
Coding Trend Analyses: Myositis Coding Trend Analyses	Coding Trend Analyses	myositis View More Outcomes (1)	06/15/2018
Coding Trend Analyses: Rhabdomyolysis Coding Trend Analyses	Coding Trend Analyses	rhabdomyolysis View More Outcomes (1)	06/15/2018
Gastrointestinal Bleed Algorithm Defined in "PROMPT: Rivaroxaban Surveillance, Gastrointestinal Bleed" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	gastrointestinal (GI) bleed View More Outcomes (1)	05/10/2018
Intracranial Hemorrhage Algorithm Defined in "PROMPT: Rivaroxaban Surveillance, Intracranial Hemorrhage" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intracranial hemorrhage View More Outcomes (1)	05/07/2018
Intussusception Algorithm Defined in "Intussusception Risk After Rotavirus Vaccination in U.S. Infants (PRISM)" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	intussusception View More Outcomes (1)	05/07/2018
Complex Regional Pain Syndrome (CRPS), Uveitis, Acute Disseminated Encephalomyelitis (ADEM), and Acute Pericarditis Algorithms Defined in "Sequential Analysis of Gardasil 9 Safety" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	acute disseminated encephalomyelitis (ADEM) , acute pericarditis , complex regional pain syndrome (CRPS) , uveitis View More Outcomes (4)	04/30/2018
Clostridium difficile Algorithm Defined in "Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Clostridium difficile Events After Use of Oral Clindamycin versus Penicillins" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	clostridium difficile View More Outcomes (1)	04/30/2018
Hypoglycemia Algorithm Defined in "Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Hypoglycemia Events After Use of Glyburide versus Glipizide" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	hypoglycemia View More Outcomes (1)	04/26/2018
Seizure Algorithm Defined in "Seizure following Ranolazine Use: A Self-Controlled Risk Interval Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	seizure View More Outcomes (1)	04/24/2018
Stroke Algorithm Defined in "Stroke following Typical or Atypical Antipsychotic Use in Non-Elderly Patients: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	hemorrhagic stroke , ischemic stroke , stroke View More Outcomes (3)	04/23/2018
Venous Thromboembolism Algorithm Defined in "Venous Thromboembolism following Continuous or Extended Cycle Contraceptive Use: A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	venous thromboembolism (VTE) View More Outcomes (1)	04/23/2018
Stroke Algorithm Defined in "Stroke following Atypical Antipsychotic or Z-Hypnotic Use in Patients with Prior Use of Selective Serotonin Reuptake Inhibitors (SSRIs): A Propensity Score Matched Analysis" Outcomes Assessed in Inferential Analyses	Outcomes Assessed in Inferential Analyses	hemorrhagic stroke , ischemic stroke , stroke View More Outcomes (3)	04/23/2018
Sentinel Medical Chart Review Gap Analysis Novel Approaches to More Efficient Outcome Validation	Novel Approaches to More Efficient Outcome Validation		04/18/2018
Mini-Sentinel: Automated Approaches to Anaphylaxis Case Classification Using Unstructured Data Novel Approaches to More Efficient Outcome Validation	Novel Approaches to More Efficient Outcome Validation	anaphylaxis View More Outcomes (1)	03/07/2018
Validation of Lymphoma in ICD-10-CM Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	lymphoma View More Outcomes (1)	02/22/2018
Influenza Vaccines and Pregnancy Outcomes (PRISM) Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	spontaneous abortion (SAB) View More Outcomes (1)	01/26/2018
Validation of Serious Infections among an Immunocompromised Population Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	serious infection View More Outcomes (1)	11/19/2017
Evaluation of New Technologies Associated with Chart Review Novel Approaches to More Efficient Outcome Validation	Novel Approaches to More Efficient Outcome Validation		08/16/2017
Thromboembolic Events After Immunoglobulin Administration Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	acute myocardial infarction (AMI) , ischemic stroke , thromboembolic events (TEE) , venous thromboembolism (VTE) View More Outcomes (4)	07/13/2017
Parenteral Iron and Anaphylactoid Reactions Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	anaphylactoid reaction View More Outcomes (1)	07/22/2016
Health Outcome Algorithm Inventory Literature Reviews	Literature Reviews	Achilles tendon rupture (ATR) , Bell’s palsy , Guillain-Barré syndrome , Henoch Schönlein purpura (HSP) , acute intracranial hemorrhage , acute ischemic stroke , acute pancreatitis , acute respiratory failure , acute stroke (ischemic or hemorrhagic) , agranulocytosis , aplastic anemia , asthma exacerbation , attempted suicide , erythema multiforme major , febrile seizure , gastrointestinal (GI) bleed , hip fracture , hypertensive emergency , idiopathic thrombocytopenic purpura , inflammatory bowel disease (IBD) , juvenile rheumatoid arthritis , neutropenia , peripheral neuropathy , premature delivery , pulmonary fibrosis , pulmonary hypertension , rhabdomyolysis , sepsis , severe acute liver injury (SALI) , spontaneous abortion (SAB) , stillbirth , sudden cardiac death , sudden or rapidly-progressing hearing loss , suicide , systemic lupus erythematosus (SLE) , thrombocytopenia , thrombotic thrombocytopenic purpura , toxic epidermal necrolysis , tuberculosis (TB) , type 1 diabetes mellitus , venous thromboembolism (VTE) View More Outcomes (41)	05/23/2016
Influenza Vaccines and Febrile Seizures (PRISM) Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	febrile seizure View More Outcomes (1)	09/18/2015
Gardasil Vaccination and Venous Thromboembolism (PRISM) Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	venous thromboembolism (VTE) View More Outcomes (1)	04/21/2015
16 Health Outcomes of Interest for Surveillance Preparedness Literature Reviews	Literature Reviews	Achilles tendon rupture (ATR) , Guillain-Barré syndrome , Henoch Schönlein purpura (HSP) , attempted suicide , erythema multiforme major , febrile seizure , hip fracture , idiopathic thrombocytopenic purpura , peripheral neuropathy , pulmonary hypertension , rhabdomyolysis , severe acute liver injury (SALI) , sudden cardiac death , suicide , thrombocytopenia , toxic epidermal necrolysis , type 1 diabetes mellitus , valvulopathy , ventricular arrhythmia View More Outcomes (19)	07/01/2014
Intussusception Risk After Rotavirus Vaccination in U.S. Infants (PRISM) Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	intussusception View More Outcomes (1)	02/03/2014
HOI Evidence Reviews (PRISM) Literature Reviews	Literature Reviews	Bell’s palsy , Henoch Schönlein purpura (HSP) , Kawasaki disease , acute bronchospasm , acute asthma , acute disseminated encephalomyelitis (ADEM) , bronchospasm , idiopathic facial palsy , intrauterine fetal demise , myocarditis , myopericarditis , optic neuritis , rheumatoid arthritis , spontaneous abortion (SAB) , stillbirth , systemic lupus erythematosus (SLE) , tic , transverse myelitis , uveitis , wheeze View More Outcomes (20)	12/25/2013
Validation of Acute Kidney Injury Cases Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	acute kidney injury View More Outcomes (1)	12/22/2013
Alternative Methods for Health Outcomes of Interest Validation Novel Approaches to More Efficient Outcome Validation	Novel Approaches to More Efficient Outcome Validation		09/25/2013
Validation of Anaphylaxis Cases Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	anaphylaxis View More Outcomes (1)	03/27/2013
Validation of Severe Liver Injury Cases Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	severe liver injury View More Outcomes (1)	01/29/2013
HOI Literature Review - Venous Thromboembolism Literature Reviews	Literature Reviews	venous thromboembolism (VTE) View More Outcomes (1)	09/04/2011
HOI Literature Review - Gap Analysis Literature Reviews	Literature Reviews	Achilles tendon rupture (ATR) , acute respiratory failure , anaphylactic shock , anaphylaxis , angioedema , atrial fibrillation , attempted suicide , cerebrovascular accident (CVA) , congestive heart failure , convulsion , depression , epilepsy , erythema multiforme major , hypersensitivity reactions , infection related to blood products, tissue grafts, or organ transplantation , interstitial lung disease , lymphoma , orthopedic implant removal and revision , pancreatitis , pulmonary fibrosis , seizure , serious cardiac arrhythmia , suicide , toxic epidermal necrolysis , transfusion-related ABO incompatibility reaction , transfusion-related septicemia , transient ischemic attack (TIA) , venous thromboembolism (VTE) View More Outcomes (30)	08/18/2011
HOI Literature Review - Hypersensitivity Reactions Literature Reviews	Literature Reviews	fever , hypersensitivity reactions View More Outcomes (2)	07/29/2011
HOI Literature Review - Orthopedic Implant Removal Literature Reviews	Literature Reviews	orthopedic implant removal and revision View More Outcomes (1)	07/19/2011
HOI Literature Review - Pulmonary Fibrosis Literature Reviews	Literature Reviews	interstitial lung disease , pulmonary fibrosis View More Outcomes (2)	07/14/2011
Validation of Acute Myocardial Infarction Cases Validations Supported by Traditional Medical Chart Review	Validations Supported by Traditional Medical Chart Review	acute myocardial infarction (AMI) View More Outcomes (1)	07/01/2011
HOI Literature Review - Atrial Fibrillation Literature Reviews	Literature Reviews	atrial fibrillation View More Outcomes (1)	06/30/2011
HOI Literature Review - Erythema Multiforme Literature Reviews	Literature Reviews	Stevens–Johnson Syndrome , erythema multiforme major , erythema multiforme minor , toxic epidermal necrolysis View More Outcomes (4)	06/16/2011
HOI Literature Review - Transfusion Sepsis Literature Reviews	Literature Reviews	transfusion-related sepsis , transfusion-related septicemia View More Outcomes (2)	06/15/2011
HOI Literature Review - Respiratory Failure Literature Reviews	Literature Reviews	acute respiratory failure View More Outcomes (1)	06/13/2011
HOI Literature Review - Anaphylaxis Literature Reviews	Literature Reviews	anaphylactic shock , anaphylaxis , angioneurotic edema View More Outcomes (3)	06/10/2011
HOI Literature Review - Seizures Literature Reviews	Literature Reviews	convulsion , epilepsy , seizure View More Outcomes (3)	06/06/2011
HOI Literature Review - CVA/TIA Literature Reviews	Literature Reviews	cerebrovascular accident (CVA) , transient ischemic attack (TIA) View More Outcomes (2)	06/02/2011
HOI Literature Review - ABO Incompatibility Literature Reviews	Literature Reviews	transfusion-related ABO incompatibility reaction View More Outcomes (1)	05/27/2011
HOI Literature Review - Lymphomas Literature Reviews	Literature Reviews	lymphoma View More Outcomes (1)	05/27/2011
HOI Literature Review- Transfusion/Graft Infections Literature Reviews	Literature Reviews	infection related to blood product , infection related to tissue graft , tissue graft View More Outcomes (3)	05/27/2011
HOI Literature Review - Pancreatitis Literature Reviews	Literature Reviews	pancreatitis View More Outcomes (1)	05/20/2011
HOI Literature Review - Cardiac Arrhythmias Literature Reviews	Literature Reviews	cardiac arrest , including ventricular fibrillation , serious cardiac arrhythmia , sudden cardiac death , supraventricular tachycardia (SVT) , torsades de pointes View More Outcomes (6)	03/02/2011
HOI Literature Review - Congestive Heart Failure Literature Reviews	Literature Reviews	congestive heart failure View More Outcomes (1)	02/08/2011
HOI Literature Review - Depression Literature Reviews	Literature Reviews	depression View More Outcomes (1)	02/08/2011
HOI Literature Review - Suicide Literature Reviews	Literature Reviews	attempted suicide , suicidal ideation , suicide View More Outcomes (3)	02/07/2011