Sentinel Initiative

Report Finder

Silver and white compass pointing towards Safety which is written in the compass.

About

Pen resting on paper with written statistics and numbers.

Medical Product Assessments

Patient vitals monitor with blurred background

Data and Surveillance Tools

Doctor writing a prescription

Communications

Network of Collaborators

Sentinel brings together public, academic and private organizations that provide access to healthcare data and expertise.

Data at a Glance

The Sentinel Distributed Database is comprised of quality-checked electronic data held by 18 partner organizations.

Statistical Methods

Sentinel explores the application of a wide range of methods to enhance medical product safety assessment.

Featured Postings

Spotlight

Posted for Public Comment: Evaluation of Three Self-Controlled Methods for Signal Detection: TreeScan, Sequence Symmetry Analysis, and Information Component Temporal Pattern Discovery

Fri, 11/30/2018
The FDA Sentinel Initiative — An Evolving National Resource

Thu, 11/29/2018
Sentinel Initiative Public Workshop & Training

Fri, 10/12/2018
Medicare Claims Synthetic Public Use Files in Sentinel Common Data Model Format

Wed, 04/25/2018

Ongoing Projects

Sequential TreeScan Signal Identification Methods Development

Tue, 12/11/2018
ARIA Tool Enhancement: Integrating TreeScan Signal Identification Capabilities

Mon, 12/10/2018
ARIA Tool Enhancement: Enabling Interrupted Time Series Analyses

Wed, 12/05/2018

Modular Programs and Summary Tables

Use of Multiple Sclerosis Drugs Among Pregnant Women

Thu, 12/06/2018
Pulmonary Arterial Hypertension and Interstitial Lung Disease Events Among Interleukin Inhibitor Users

Mon, 12/03/2018

Data and Tools

Routine Querying System Documentation (version 7.0.0)

Fri, 11/02/2018
Sentinel Common Data Model v7.0.0

Wed, 10/31/2018
Data Quality Review and Characterization Programs v4.1.0

Wed, 02/28/2018