Sentinel Initiative

Report Finder

Silver and white compass pointing towards Safety which is written in the compass.

About

Pen resting on paper with written statistics and numbers.

Medical Product Assessments

Patient vitals monitor with blurred background

Data and Surveillance Tools

Doctor writing a prescription

Communications

Network of Collaborators

Sentinel brings together public, academic and private organizations that provide access to healthcare data and expertise.

Data at a Glance

The Sentinel Distributed Database is comprised of quality-checked electronic data held by 18 partner organizations.

Statistical Methods

Sentinel explores the application of a wide range of methods to enhance medical product safety assessment.

Featured Postings

Spotlight

35th International Conference on Pharmacoepidemiology and Therapeutic Risk Management

Wed, 09/04/2019
Sentinel Query Builder Standalone Application

Mon, 08/19/2019
Medicare Claims Synthetic Public Use Files in Sentinel Common Data Model Format

Wed, 03/27/2019
SAS Code for Transforming the IBM MarketScan® Research Databases (MarketScan) into the Sentinel Common Data Model

Wed, 01/30/2019

Publications and Presentations

Identification of Potential Drug Name Confusion Errors in the Sentinel System

Wed, 09/04/2019
First-Trimester Exposure to Gadolinium-based Contrast Agents: A Utilization Study of 4.6 Million U.S. Pregnancies

Thu, 08/22/2019
Development of an Algorithm to Detect Methotrexate Wrong Frequency Error Using Computerized Health Care Data

Tue, 08/13/2019

Modular Programs and Summary Tables

Multiple Sclerosis Relapses among Copaxone, Glatopa, Gilenya, and Glatiramer Users

Tue, 09/17/2019
Cutaneous Small Vessel Vasculitis and Acute Kidney Injury Following Direct-Acting Oral Anticoagulant Use

Mon, 09/16/2019
Non-Melanoma Skin Cancer following Hydrochlorothiazide Use

Fri, 09/13/2019
Sinus Stents with Mometasone and Diminished Visual Acuity

Thu, 09/12/2019
Use of Angiotensin-Converting Enzyme (ACE) Inhibitors and Angiotensin Receptor Blockers (ARB) in a Pediatric Population

Thu, 08/22/2019
Utilization Patterns of Qsymia (Phentermine/Topiramate)

Wed, 08/07/2019
Use of Higher Dosage Strength Oral and Transmucosal Opioid Analgesics

Wed, 07/31/2019

Data and Tools

Routine Querying System (version 8.1.1)

Mon, 09/16/2019
Coding Trend Analyses

Mon, 08/26/2019
Data Quality Review and Characterization Programs v5.0.1

Thu, 05/30/2019
Sentinel Common Data Model v7.0.0

Wed, 10/31/2018

Final Results and Reports

Transfusion-Related Acute Lung Injury after Red Blood Cell, Plasma, and Platelet Administration 2013-2015

Wed, 09/11/2019

Analytic Packages

Neuropsychiatric Events following Montelukast Use: A Propensity Score Matched Analysis

Mon, 08/19/2019
Osteoporotic Fractures following Lupron Depot-PED Use: A Multiple Factor Matched Analysis

Tue, 07/02/2019