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Mini-Sentinel: Developing, Implementing, and Testing a Program for High-Dimensional Propensity Score Adjustment in the Mini-Sentinel Distributed Data Environment

Basic Details
Date Posted
Status
Complete
Description

This report summarizes an assessment of the feasibility of incorporating propensity score (PS) and hd-PS adjustment in the Mini-Sentinel distributed environment. The project included development of a new module that allows users to select a range of PS and hd-PS related parameters and outputs analytic datasets with corresponding tables, figures, and other diagnostic information. The new module is fully compatible with the Mini-Sentinel Common Data Model (MSCDM).

Deliverable(s) (1)
Mini-Sentinel High-Dimensional Propensity Score Adjustment
Workgroup Leader(s)

Joshua J Gagne, PharmD, ScD; Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA

Workgroup Member(s)

Shirley V. Wang, PhD, ScM; Jeremy Rassen, ScD; Sebastian Schneeweiss, MD, ScD; Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA

Nicolas Beaulieu, MA; Jeffrey S. Brown, PhD; Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA