Details
Pregnant women are at high risk for developing severe illness related to coronavirus disease 2019 (COVID-19). We adapted the “COVID-19 infectiOn aNd medicineS In pregnancy” (CONSIGN) study protocol as part of an international collaboration to examine medication use patterns among pregnancies in the United States.
We identified eligible women aged 12–55 years with documented live-birth deliveries in the Sentinel Distributed Database (SDD) who had at least one qualifying diagnosis for COVID-19 or a positive-confirmed test for SARS-CoV-2, by trimester of COVID-19 infection. We conducted two sets of analyses comparing medication groups and COVID-19 treatment utilization in the 30 days prior to or after COVID-19 among pregnancies with COVID-19 to: (1) pregnancies without COVID-19 during six months prior to or during pregnancy; and (2) non-pregnancy episodes with COVID-19.