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Dihydropyrimidine Dehydrogenase Gene Testing and Fluoropyrimidine Treatment in the United States – a Sentinel Distributed Database Study

Basic Details
Date
Type
Presentation
Description

This poster describes a project that assessed whether patients received dihydropyrimidine dehydrogenase (DPYD) gene testing genetic testing before or after initiation of fluoropyrimidines. It was presented at the 2026 ISPE Annual Meeting. 

Materials

Dihydropyrimidine Dehydrogenase Gene Testing and Fluoropyrimidine Treatment in the United States – a Sentinel Distributed Database Study

Information
Host

International Society for Pharmacoepidemiology

Related Assessment(s)
Sentinel Drug Study: Fluoropyrimidines & Dihydropyrimidine Dehydrogenase Testing
Sentinel Drug Analysis: Dihydropyrimidine Dehydrogenase (DPYD) Gene Variant Testing Rates and Fluoropyrimidine Use Following Pharmacogenetic Testing Among Incident Fluoropyrimidine Users: A Descriptive Analysis
2026 ISPE Annual Meeting
Presenter(s)

Jamal Jones

Author(s)

Jamal Jones, Fatma M. Shebl, Ashish Rai, Amelia Thyen, Diane Emerton, Lexie Jaquish, Lisa Kalman, Yang Xia, Diego Arambula, J Rex Astles, Robert Schuck, Michael Pacanowski