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The Role of Hemoglobin Laboratory Test Results for the Detection of Upper Gastrointestinal Bleeding Outcomes Resulting from the Use of Medications in Observational Studies

    Basic Details
    Medical Product
    non-steroidal anti-inflammatory drug (NSAID)
    Health Outcome(s)
    gastrointestinal hemorrhage
    perforated ulcer

    The objective of this study was to evaluate whether hemoglobin results increase UGI outcome identification in electronic databases, using non-steroidal anti-inflammatory drugs (NSAIDs) as a test case.


    Elisabetta Patorno MD, DrPH, Joshua Gagne PharmD, ScD, Christine Lu PhD, MSc, Kevin Haynes PharmD, MSCE, Andrew Sterret PhD, Jason Roy PhD, Marsha Raebel PharmD, Xingmei Wang MS

    Corresponding Author

    E. Patorno, Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine Brigham and Women’s Hospital and Harvard Medical School, Boston, USA. Email: