Validity of Diagnostic Codes to Identify Cases of Severe Acute Liver Injury in the U.S. Food and Drug Administration's Mini-Sentinel Distributed Database

Project Title Validity of Diagnostic Codes to Identify Cases of Severe Acute Liver Injury in the U.S. Food and Drug Administration's Mini-Sentinel Distributed Database
Date
Tuesday, June 25, 2013
Location

Pharmacoepidemiology and Drug Safety, Volume 22, Issue 8, August 2013, Pages 861–872, DOI: 10.1002/pds.3470

Description

This article describes a Mini-Sentinel project to validate an algorithm based on International Classification of Diseases, Ninth revision, Clinical Modification (ICD-9-CM) codes for severe acute liver injury (SALI) among health plan members in the Mini-Sentinel Distributed Database (MSDD) for patients without liver/biliary disease and for those with chronic liver disease (CLD), using medical record review.

Health Outcome
chronic liver disease
severe acute liver injury (SALI)
Time Period
January 1, 2009 - December 31, 2010
Corresponding Author

V. L. Re III, MD, MSCE, Center for Clinical Epidemiology and Biostatistics, 836 Blockley Hall, 423 Guardian Drive, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6021, USA. Email: vincentl@mail.med.upenn.edu

Authors

Vincent Lo Re MD, MSCE; Kevin Haynes PharmD, MSCE; David Goldberg MD, MSCE; Kimberly L. Forde MD, MHS; Dena M. Carbonari MS; Kimberly B. F. Leidi MPH; Sean Hennessy PharmD, PhD; K. Rajender Reddy MD; Pamela A. Pawloski PharmD; Gregory W. Daniel PhD, MPH, RPh; Craig Cheetham PharmD, MS; Aarthi Iyer MPH; Kara O. Coughlin; Sengwee Toh ScD, Denise M. Boudreau RPh, PhD; Nandani Selvam PhD, MPH; William O. Cooper MD, MPH; Mano S. Selvan PhD; Jeffery J. VanWormer PhD; Mark I. Avigan MD, CM; Monika Houstoun PharmD; Gwen L. Zornberg MD, ScD, MS; Judith A. Racoosin MD, MPH; Azadeh Shoaibi PhD, MHS, MS

Data Sources
Mini-Sentinel Distributed Database (MSDD)
Related Assessments
Validation of Severe Liver Injury Cases
Publication Type
Publication
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