Two-Dimensional Scan Statistics for Assessing Vaccine Safety in Pregnancy (PRISM)

Project Title Two-Dimensional Scan Statistics for Assessing Vaccine Safety in Pregnancy (PRISM)
Date Posted
Wednesday, April 27, 2016
Status
Complete
Deliverables
Description

Methods project including two simulation studies to: 

  1. Evaluate the performance of (1-dimensional) temporal scan statistics under various scenarios, and
  2. evaluate the performance of a 2-dimensional temporal scan statistic under alternative assumptions about pregnancy outcomes
Workgroup Leader(s)

Lingling Li PhD; Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA

Wei Hua MD, PhD; Lihan Yan PhD; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD 

Workgroup Members

Sophia Axtman; Sandra Feibelmann MPH; Alison Kawai ScD; Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA

Gabriela Vazquez Benitez PhD, MSc; HealthPartners Institute for Education and Research, Minneapolis, MN 

Stan Xu PhD; Kaiser Permanente Institute for Health Research, Colorado, Denver, CO 

Data Sources
Mini-Sentinel Distributed Database (MSDD)