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Brand to Generic Switching Patterns Among Advair Diskus Users with Asthma or Chronic Obstructive Pulmonary Disease (COPD): A Descriptive Analysis

    Basic Details
    Date Posted
    Status
    Complete
    Medical Product
    Advair Diskus
    fluticasone salmeterol
    Health Outcome(s)
    brand to generic switching
    Description

    In this request we assessed switching patterns among Inhaled Corticosteroids (ICS)/ Long-acting Beta-agonists (LABA) users with prior asthma or chronic obstructive pulmonary disease (COPD) and without recent history of pneumonia in the Sentinel Distributed Database (SDD). We performed a post-hoc analysis to plot the cumulative incidence of switching function for each pattern, which could account for treatment cessation as a competing risk for switching.

    The study period includes data from February 1, 2019 up to December 31, 2020. We distributed this request to seven Sentinel Data Partners on September 7, 2021.

    Additional Details
    FDA Center
    CDER
    Time Period
    February 1, 2019 - December 31, 2020
    Analysis Type
    Descriptive
    Population / Cohort
    Individuals 4 years of age and older
    Data Sources
    Sentinel Distributed Database (SDD)