Osteoporotic Fractures Following Lupron Depot-PED Use: A Multiple Factor Matched Analysis

Basic Details
Date Posted
Monday, July 1, 2019
Status
In progress
Medical Product
Lupron Depot-PED
Health Outcome(s)
fracture
hip replacement
osteoporotic fracture
temporomandibular joint replacement
Description

This analysis investigates whether children with centralized precocious puberty (CPP) who are exposed to Lupron Depot-PED are at higher risk for fractures compared to children who are unexposed to Lupron Depot-PED in the Sentinel Distributed Database.

The primary outcome assessed in this analysis is osteoporotic fractures. The secondary outcomes are any fracture, hip replacement, and temporomandibular joint replacement.

The analytic package associated with this analysis can be found externally in Sentinel's Git Repository located here. The Git Repository serves as Sentinel's version control tracking system for analytic packages and technical documentation.