TabsDetailsBasic DetailsDate Posted: Thursday, March 5, 2020Status: CompleteMedical Product: hydrochlorothiazide (HCTZ)Health Outcome(s): non-melanoma skin cancerDescription: In this report we examined the association between exposure to hydrochlorothiazide (HCTZ)-containing products and incidence of non-melanoma skin cancer (NMSC) in the Sentinel Distributed Database (SDD). We distributed this request to 17 Sentinel Data Partners. The study period included data from January 1, 2000 to August 31, 2018.The analytic packages associated with this analysis can be found externally in Sentinel's Git Repository located here. The Git Repository serves as Sentinel's version control tracking system for analytic packages and technical documentation. Read More Deliverables (2)Sentinel Modular Program Report: Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched AnalysisSentinel Analytic Packages: Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched AnalysisAdditional InformationAdditional DetailsFDA Center: CDERTime Period: January 1, 2000 - August 31, 2018Study Type: Modular ProgramAssessment Type: Safety AnalysesPopulation / Cohort: All individualsData Sources: Sentinel Distributed Database (SDD)Related Links: Basal Cell Carcinoma Algorithm Defined in "Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched Analysis"Squamous Cell Carcinoma Algorithm Defined in "Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched Analysis"Hydrochlorothiazide Use and Risk of Non-Melanoma Skin CancerNon-Melanoma Skin Cancer following Hydrochlorothiazide UseDuration of Use Among New Users of Hydrochlorothiazide (HCTZ), Angiotensin-Converting Enzyme Inhibitors (ACEIs), and Angiotensin II Receptor Blockers (ARBs)Hydrochlorothiazide Use and Risk of Non-Melanoma Skin Cancer2020 ICPE Presentation: Risk of Non-Melanoma Skin Cancer Associated with Hydrochlorothiazide-Containing Products in the United StatesRisk of Non-Melanoma Skin Cancer in Association with Use of Hydrochlorothiazide-Containing Products in the United States