Antipsychotics/SSRIs and Stroke (PSM)

Project Title Antipsychotics/SSRIs and Stroke (PSM)
Date Posted
Thursday, November 2, 2017
Project ID
cder_mpl2p_wp005
Status
Complete
Deliverables
Related Links
Description

This request investigated the association between selective serotonin reuptake inhibitors (SSRIs) users who initiate atypical antipsychotic use and the occurrence of stroke. Data from January 1, 2001 to September 30, 2015 from 10 Data Partners contributing to the Sentinel Distributed Database were included in this report. This request was distributed to Data Partners on April 14, 2017.

  • Report 1: Association between selective serotonin reuptake inhibitors (SSRIs) users who initiate the atypical antipsychotic olanzapine and the occurrence of stroke
  • Report 2: Association between selective serotonin reuptake inhibitors (SSRIs) users who initiate the atypical antipsychotic quetiapine and the occurrence of stroke
  • Report 3: Association between selective serotonin reuptake inhibitors (SSRIs) users who initiate the atypical antipsychotic risperidone and the occurrence of stroke
  • Report 4: Association between selective serotonin reuptake inhibitors (SSRIs) users who initiate the atypical antipsychotic aripiprazole and the occurrence of stroke
  • Report 5: Association between selective serotonin reuptake inhibitors (SSRIs) users who initiate any atypical antipsychotic and the occurrence of stroke
  • Report 6: Association between fluoxetine (a specific selective serotonin reuptake inhibitor (SSRI) users who initiate the atypical antipsychotic olanzapine and the occurrence of stroke.
Medical Product
aripiprazole
fluoxetine
olanzapine
quetiapine
risperidone
Health Outcome
stroke
Population / Cohort
All individuals 18 - 64 years of age
Time Period
January 1, 2001 - September 30, 2015
Assessment Type
Exploratory Analyses
Study Type
Modular Program
Data Sources
Sentinel Distributed Database (SDD)
FDA Center
CDER