Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched Analysis

Project Title Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched Analysis
Date Posted
Friday, March 6, 2020
Project ID
cder_mpl2p_wp016, cder_mpl1p_wp034, cder_mpl2p_wp019, cder_mpl2p_wp022
Status
Complete
Deliverables
Related Links
Description

In this report we examined the association between exposure to hydrochlorothiazide (HCTZ)-containing products and incidence of non-melanoma skin cancer (NMSC) in the Sentinel Distributed Database (SDD). We distributed this request to 17 Sentinel Data Partners. The study period included data from January 1, 2000 to August 31, 2018.

The analytic packages associated with this analysis can be found externally in Sentinel's Git Repository located here. The Git Repository serves as Sentinel's version control tracking system for analytic packages and technical documentation.

Medical Product
hydrochlorothiazide (HCTZ)
Health Outcome
non-melanoma skin cancer
Population / Cohort
All individuals
Time Period
January 1, 2000 - August 31, 2018
Assessment Type
Safety Analyses
Study Type
Modular Program
Data Sources
Sentinel Distributed Database (SDD)
FDA Center
CDER