This statistical methods project is one of four workgroups that used exposure/outcome pairs with known positive associations to test Mini-Sentinel (now Sentinel) routine querying tools. Specifically, these known positive associations tested the Cohort Identification and Descriptive Analysis (CIDA) tool in combination with the Propensity Score Analysis (PSA) tool.
This known positive test case assessed severe hypoglycemia events following new use of glyburide versus glipizide. The query was run against the Sentinel Distributed Database (SDD) for the time period of January 1, 2008 to September 30, 2014. The queries were distributed in February 2015.
Report 1 contains results for severe hypoglycemia events in any diagnosis position for emergency department encounters or first-listed diagnosis for inpatient encounters. This report includes results from the 5 Data Partners for which the high-dimensional propensity score (hdPS) analysis ran successfully and converged.
Report 2 contains results for severe hypoglycemia events in any diagnosis position for emergency department encounters or first-listed diagnosis for inpatient encounters. This report includes results from 13 Data Partners.
Report 3 contains results for severe hypoglycemia events in any diagnosis position for emergency department encounters only. This report includes results from the 5 Data Partners for which the high-dimensional propensity score (hdPS) analysis ran successfully and converged.
Report 4 contains results for severe hypoglycemia events in any diagnosis position for emergency department encounters only. This report includes results from 13 Data Partners.
