Routine Querying Tools (Modular Programs)

This section provides detailed information about the technical aspects of Sentinel’s routine querying tools. For a less technical overview, please see Active Risk Identification and Analysis (ARIA).

Sentinel’s routine querying tools include modular programs, summary tables, and software toolkits. The latest versions of these tools are posted on the Sentinel website. For information concerning older versions of the tools, contact the Sentinel Operations Center.

Modular programs are grouped into three levels: Level 1 modular program queries identify cohorts of interest and, for some cohorts, can perform unadjusted and minimally adjusted (i.e., by Data Partner, age group, sex, and year) analyses. Level 2 modular program queries identify cohorts of interest, perform more complex adjustment for confounding, and generate effect estimates and confidence intervals. Level 3 modular program queries identify cohorts of interest and perform more complex adjustment for confounding repeatedly as part of prospective sequential analysis. The below tables provide a description of the cohort identification strategies available within each modular program level along with a link to specific information on the querying tool used to conduct an analysis using that strategy.

Summary Table Queries are very simple queries on counts, prevalence, and incidence of drug products, diagnosis codes, and procedure codes stratified by year, sex, age group, and where appropriate, setting of care.

Level 1 Modular Program Queries

Level 2 Modular Program Queries

Level 3 Modular Program Queries

Summary Table Queries

Title Statussort descending Date Posted
Modular Program 8: Uptake, Use, and Persistence of New Molecular Entities (NMEs) Complete 6/27/2014
Sentinel Distributed Query Tool Complete 6/29/2016
Distributed Query Tool Summary Table Descriptions Complete 6/24/2016
Summary Table V2 Programming Specifications Complete 6/24/2016
Technical Discussion of Summary Table V2 Package Complete 6/24/2016
Summary Tables SAS Package Complete 6/24/2016
Summary Tables Programming Package V2 Investigator Release Notes Complete 6/24/2016
Routine Querying System Complete 12/27/2016
Modular Program 4: Frequency of Select Events During Concomitant Exposure to a Drug/Procedure Groups of Interest Complete 6/11/2014
Modular Program 7: Drug Use, Medical Diagnoses, and Medical Procedures Before and After an Exposure or Event of Interest Complete 6/11/2014
Modular Program 1: Characterization of Use of Medical Product Exposures Retired 11/27/2012
Modular Program 2: Characterization of Use of Medical Product Exposures among Individuals with or without Condition(s) of Interest Retired 3/10/2013
Modular Program 3: Frequency of Select Events During Exposure to a Drug/Procedure Group of Interest Retired 7/14/2014
Modular Program 5: Background Rates for Health Outcomes of Interest Retired 3/10/2013
Modular Program 6: Frequency and Duration of Treatment Following an Event of Interest Retired 6/11/2014
Modular Program 9: Background Rates and Characterization of Health Outcomes of Interest among Individuals with or without Condition(s) of Interest Retired 6/11/2014