Health Outcomes of Interest

This webpage provides access to Sentinel Health Outcome of Interest (HOI) activities that have been conducted by the FDA. The search below can be used to find more information about each study type or health outcome. Code lists (such as ICD-9-CM codes, ICD-10 codes, procedure codes, etc.), algorithm criteria, and literature reviews for these activities appear in the form of reports or Microsoft Excel workbooks.

These materials can be found by clicking on the hyperlinked Title to navigate to the activity’s webpage which also lists the Deliverables.
 

  • Novel Approaches to More Efficient Outcome Validation
    • Aim to identify solutions to the governance, process, and technology barriers to support more efficient outcome validation as a starting point for greater sufficiency of Active Risk Identification and Analysis (ARIA), a stronger Sentinel System, and a more rigorous evidence generation enterprise.
  • Validations Supported by Traditional Medical Chart Review
    • Involve checking codes derived from electronic medical records and administrative claims-based data against medical chart information to verify that the electronic codes validly and reliably identify individuals with particular medical conditions.
  • Outcomes Assessed in Inferential Analyses
    • Identify medical conditions defined as outcomes of interest in inferential analyses and their respective code lists and algorithm criteria.
  • Coding Trend Analyses
    • Display the trends for outcome definitions across the ICD-9-CM and ICD-10-CM/PCS eras.
  • Literature Reviews
    • ​​​​​​​Primarily concern identification of health outcomes and focus on determining which codes in electronic medical record and administrative claims-based data are the most valid and reliable indicators of the presence of particular medical conditions.

Search Health Outcomes of Interest

Title Outcomes Date
Nasal Septal Perforation Defined in "Glaucoma, Cataracts, Diminished Visual Acuity, and Nasal Septal Perforation following Mometasone Sinus Implant Use in Patients with Nasal Polyposis: A Descriptive Analysis"
Outcomes Assessed in Inferential Analyses
nasal septal perforation
08/05/2020
Glaucoma Defined in "Glaucoma, Cataracts, Diminished Visual Acuity, and Nasal Septal Perforation following Mometasone Sinus Implant Use in Patients with Nasal Polyposis: A Descriptive Analysis"
Outcomes Assessed in Inferential Analyses
glaucoma
08/05/2020
Diminished Visual Acuity Defined in "Glaucoma, Cataracts, Diminished Visual Acuity, and Nasal Septal Perforation following Mometasone Sinus Implant Use in Patients with Nasal Polyposis: A Descriptive Analysis"
Outcomes Assessed in Inferential Analyses
diminished visual acuity
08/05/2020
Cataracts Defined in "Glaucoma, Cataracts, Diminished Visual Acuity, and Nasal Septal Perforation following Mometasone Sinus Implant Use in Patients with Nasal Polyposis: A Descriptive Analysis"
Outcomes Assessed in Inferential Analyses
cataracts
08/05/2020
Congenital Cardiac Malformations Algorithm Defined in "Risk of Congenital Cardiac Malformations Following Armodafinil or Modafinil Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
congenital cardiac malformations
07/30/2020
Salpingectomy Algorithm Defined in "Gynecologic Surgery following Permanent Sterilization: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
salpingectomy
07/23/2020
Hysterectomy Algorithm Defined in "Gynecologic Surgery following Permanent Sterilization: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
hysterectomy
07/23/2020
Validation of Stillbirth in ICD-10-CM Post-Hoc Analyses
Validations Supported by Traditional Medical Chart Review
stillbirth
06/03/2020
Coding Trend Analyses: Alzheimer's Disease
Coding Trend Analyses
Alzheimer's disease
06/03/2020
Coding Trend Analyses: Epilepsy - Emergency Department Care Setting
Coding Trend Analyses
epilepsy
06/03/2020
Coding Trend Analyses: Epilepsy - Inpatient Care Setting
Coding Trend Analyses
epilepsy
06/03/2020
Coding Trend Analyses: Angioedema
Coding Trend Analyses
angioedema
01/28/2020
Coding Trend Analyses: Diabetes
Coding Trend Analyses
diabetes
01/28/2020
Coding Trend Analyses: Acute Myocardial Infarction
Coding Trend Analyses
acute myocardial infarction (AMI)
01/28/2020
Coding Trend Analyses: Hypertension
Coding Trend Analyses
hypertension
01/22/2020
Coding Trend Analyses: Hodgkin's Lymphoma
Coding Trend Analyses
Hodgkin's lymphoma
12/09/2019
Coding Trend Analyses: Non-Hodgkin's Lymphoma
Coding Trend Analyses
non-Hodgkin's lymphoma
11/26/2019
Coding Trend Analyses: Pulmonary Arterial Hypertension
Coding Trend Analyses
pulmonary arterial hypertension
11/26/2019
Coding Trend Analyses: Alveolar Proteinosis
Coding Trend Analyses
alveolar proteinosis
11/26/2019
Coding Trend Analyses: Interstitial Lung Disease
Coding Trend Analyses
interstitial lung disease
11/26/2019
Coding Trend Analyses: Macrophage Activation Syndrome
Coding Trend Analyses
macrophage activation syndrome
11/26/2019
Coding Trend Analyses: Adult-Onset Still's Disease
Coding Trend Analyses
adult-onset Still's disease
11/26/2019
Coding Trend Analyses: Systemic Juvenile Idiopathic Arthritis
Coding Trend Analyses
systemic juvenile idiopathic arthritis
11/26/2019
Coding Trend Analyses: Acute Pancreatitis
Coding Trend Analyses
acute pancreatitis
11/01/2019
Coding Trend Analyses: Serious Infections
Coding Trend Analyses
serious infection
11/01/2019
Coding Trend Analyses: Anaphylaxis
Coding Trend Analyses
anaphylaxis
10/30/2019
Coding Trend Analyses: Hospitalized Influenza
Coding Trend Analyses
hospitalized influenza
10/11/2019
Coding Trend Analyses: Gastrointestinal Bleed
Coding Trend Analyses
gastrointestinal (GI) bleed
10/11/2019
Coding Trend Analyses: Head Injury
Coding Trend Analyses
head injury
09/27/2019
Coding Trend Analyses: Syncope
Coding Trend Analyses
syncope
09/27/2019
Coding Trend Analyses: Poisoning
Coding Trend Analyses
poisoning
09/27/2019
Coding Trend Analyses: Brain Tumor
Coding Trend Analyses
brain tumor
09/27/2019
Coding Trend Analyses: Kidney Disease
Coding Trend Analyses
kidney disease
09/27/2019
Transfusion-Related Acute Lung Injury After Red Blood Cell, Plasma, and Platelet Administration 2013-2015
Validations Supported by Traditional Medical Chart Review
transfusion-related acute lung injury (TRALI)
09/09/2019
Coding Trend Analyses: Dialysis
Coding Trend Analyses
dialysis
09/06/2019
Coding Trend Analyses: Kidney Replacement
Coding Trend Analyses
kidney replacement
09/04/2019
Coding Trend Analyses: Stillbirth - Outpatient Care Setting
Coding Trend Analyses
stillbirth
08/30/2019
Coding Trend Analyses: Joint Replacement
Coding Trend Analyses
joint replacement
08/29/2019
Coding Trend Analyses: Valve Replacement
Coding Trend Analyses
valve replacement
08/27/2019
Coding Trend Analyses: Stillbirth - Inpatient Care Setting
Coding Trend Analyses
stillbirth
08/27/2019
Coding Trend Analyses: Ischemic Stroke
Coding Trend Analyses
ischemic stroke
08/26/2019
Coding Trend Analyses: Pulmonary Embolism
Coding Trend Analyses
pulmonary embolism
08/26/2019
Coding Trend Analyses: Mitral Stenosis
Coding Trend Analyses
mitral stenosis
08/26/2019
Coding Trend Analyses: Intracranial Hemorrhage
Coding Trend Analyses
intracranial hemorrhage
08/26/2019
Coding Trend Analyses: Gastrointestinal Hemorrhage
Coding Trend Analyses
gastrointestinal hemorrhage
08/22/2019
Coding Trend Analyses: Deep Vein Thrombosis
Coding Trend Analyses
deep vein thrombosis
08/21/2019
Suicide Algorithm Defined in "Neuropsychiatric Events following Montelukast Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
suicide
08/19/2019
Self-Harm Algorithms Defined in "Neuropsychiatric Events following Montelukast Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
self-harm
08/19/2019
Outpatient Depressive Disorder Algorithm Defined in "Neuropsychiatric Events following Montelukast Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
outpatient depressive disorder
08/19/2019
Inpatient Depressive Disorder Algorithm Defined in "Neuropsychiatric Events following Montelukast Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
inpatient depressive disorder
08/19/2019
Coding Trend Analyses: Atrial Fibrillation
Coding Trend Analyses
atrial fibrillation
08/09/2019
Coding Trend Analyses: Non-Thyroid Endocrine Cancers
Coding Trend Analyses
non-thyroid endocrine cancer
07/12/2019
Coding Trend Analyses: Convulsions - Inpatient Care Setting
Coding Trend Analyses
convulsion
07/10/2019
Coding Trend Analyses: Convulsions - Emergency Department Care Setting
Coding Trend Analyses
convulsion
07/10/2019
Temporomandibular Joint Replacement Algorithm Defined in "Osteoporotic Fractures following Lupron Depot-PED Use: A Multiple Factor Matched Analysis"
Outcomes Assessed in Inferential Analyses
temporomandibular joint replacement
07/02/2019
Hip Replacement Algorithm Defined in "Osteoporotic Fractures following Lupron Depot-PED Use: A Multiple Factor Matched Analysis"
Outcomes Assessed in Inferential Analyses
hip replacement
07/02/2019
Fracture Algorithm Defined in "Osteoporotic Fractures following Lupron Depot-PED Use: A Multiple Factor Matched Analysis"
Outcomes Assessed in Inferential Analyses
fracture
07/02/2019
Osteoporotic Fracture Algorithm Defined in "Osteoporotic Fractures Following Lupron Depot-PED Use: A Multiple Factor Matched Analysis"
Outcomes Assessed in Inferential Analyses
osteoporotic fracture
07/02/2019
Squamous Cell Carcinoma Algorithm Defined in "Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
squamous cell carcinoma
06/11/2019
Basal Cell Carcinoma Algorithm Defined in "Non-Melanoma Skin Cancer following Hydrochlorothiazide Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
basal cell carcinoma
06/11/2019
Development of a Chart Validation Table
Novel Approaches to More Efficient Outcome Validation
05/02/2019
Validation of Acute Pancreatitis Using Machine Learning and Multi-Site Adaptation for Anaphylaxis
Novel Approaches to More Efficient Outcome Validation
acute pancreatitis
04/30/2019
Coding Trend Analyses: Lymphoma
Coding Trend Analyses
lymphoma
04/25/2019
Coding Trend Analysis: Leukemia
Coding Trend Analyses
leukemia
04/25/2019
Coding Trend Analyses: Kidney and Pelvis Cancer
Coding Trend Analyses
kidney and pelvis cancer
04/25/2019
Coding Trend Analyses: Lung Cancer
Coding Trend Analyses
lung cancer
04/25/2019
Coding Trend Analyses: Endometrial Cancer
Coding Trend Analyses
endometrial cancer
04/25/2019
Coding Trend Analyses: Esophageal Cancer
Coding Trend Analyses
esophageal cancer
04/25/2019
Severe Uterine Bleed with Transfusion Management Algorithm Defined in "Severe Uterine Bleed following Novel Oral Anticoagulants Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
severe uterine bleed
04/18/2019
Severe Uterine Bleed with Surgical Management Algorithm Defined in "Severe Uterine Bleed following Novel Oral Anticoagulants Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
severe uterine bleed
04/18/2019
Coding Trend Analyses: Heart Failure
Coding Trend Analyses
heart failure
04/16/2019
Coding Trend Analyses: Nasal Septal Perforations
Coding Trend Analyses
nasal septal perforation
04/16/2019
Coding Trend Analyses: Nasal Polyps
Coding Trend Analyses
nasal polyps
04/16/2019
Coding Trend Analyses: Glaucoma
Coding Trend Analyses
glaucoma
04/16/2019
Coding Trend Analyses: Cataracts
Coding Trend Analyses
cataracts
04/16/2019
Coding Trend Analyses: Diabetes Mellitus with Pregnancy
Coding Trend Analyses
diabetes mellitus with pregnancy
04/15/2019
Coding Trend Analyses: Visual Acuity
Coding Trend Analyses
visual acuity
04/15/2019
Coding Trend Analyses: Blindness
Coding Trend Analyses
blindness
04/15/2019
Coding Trend Analyses: Urinary Bladder Cancer
Coding Trend Analyses
urinary bladder cancer
04/12/2019
Coding Trend Analyses: Pancreatic Cancer
Coding Trend Analyses
pancreatic cancer
04/12/2019
Coding Trend Analyses: Non-Melanoma Skin Cancer
Coding Trend Analyses
non-melanoma skin cancer
04/09/2019
Coding Trend Analyses: Malignant Melanoma Cancer
Coding Trend Analyses
malignant melanoma cancer
04/09/2019
Coding Trend Analyses: Type 2 Diabetes Mellitus
Coding Trend Analyses
type 2 diabetes mellitus
04/09/2019
Coding Trend Analyses: Type 1 Diabetes Mellitus
Coding Trend Analyses
type 1 diabetes mellitus
04/09/2019
Coding Trend Analyses: Diabetic Ketoacidosis
Coding Trend Analyses
diabetic ketoacidosis
04/09/2019
Coding Trend Analyses: Allergic Reactions
Coding Trend Analyses
allergic reaction
04/05/2019
Coding Trend Analyses: Ischemic Heart Disease
Coding Trend Analyses
ischemic heart disease
04/05/2019
Coding Trend Analyses: Guillain-Barré Syndrome
Coding Trend Analyses
Guillain-Barré syndrome
04/03/2019
Coding Trend Analyses: Prostate Cancer
Coding Trend Analyses
prostate cancer
04/03/2019
Coding Trend Analyses: Anaphylaxis after Vaccination
Coding Trend Analyses
anaphylaxis
04/03/2019
Coding Trend Analyses: Bell's Palsy
Coding Trend Analyses
Bell’s palsy
04/03/2019
Coding Trend Analyses: Febrile Seizures
Coding Trend Analyses
febrile seizure
04/03/2019
Acute Myocardial Infarction Algorithm Defined in "Acute Myocardial Infarction and Heart Failure following Saxagliptin or Sitagliptin Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
acute myocardial infarction (AMI)
04/01/2019
Heart Failure Algorithm Defined in "Acute Myocardial Infarction and Heart Failure Following Saxagliptin or Sitagliptin Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
heart failure
04/01/2019
Coding Trend Analyses: Rectal Cancer
Coding Trend Analyses
rectal cancer
03/29/2019
Coding Trend Analyses: Thyroid Cancer
Coding Trend Analyses
thyroid cancer
03/29/2019
Coding Trend Analyses: Female Breast Cancer
Coding Trend Analyses
female breast cancer
03/28/2019
Coding Trend Analyses: Male Breast Cancer
Coding Trend Analyses
male breast cancer
03/28/2019
Coding Trend Analyses: Anal Cancer
Coding Trend Analyses
anal cancer
03/28/2019
Coding Trend Analyses: Cervical Cancer
Coding Trend Analyses
cervical cancer
03/28/2019
Coding Trend Analyses: Colon Cancer
Coding Trend Analyses
colon cancer
03/28/2019
Coding Trend Analyses: Gout
Coding Trend Analyses
gout
03/28/2019
Coding Trend Analyses: Intracranial Hemorrhage - Inpatient Care Setting
Coding Trend Analyses
intracranial hemorrhage
03/01/2019
Coding Trend Analyses: Gestational Diabetes Mellitus
Coding Trend Analyses
gestational diabetes mellitus
03/01/2019
Coding Trend Analyses: Intracranial Hemorrhage - Any Care Setting
Coding Trend Analyses
intracranial hemorrhage
03/01/2019
Coding Trend Analyses: Lower Limb Amputation
Coding Trend Analyses
lower limb amputation
03/01/2019
Ischemic Stroke Algorithm Defined in "Stroke, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Apixaban or Warfarin Use in Patients with Non-Valvular Atrial Fibrillation: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
ischemic stroke
02/15/2019
Intracranial Hemorrhage Algorithm Defined in "Stroke, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Apixaban or Warfarin Use in Patients with Non-Valvular Atrial Fibrillation: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
intracranial hemorrhage
02/15/2019
Gastrointestinal Bleed Algorithm Defined in "Stroke, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Apixaban or Warfarin Use in Patients with Non-Valvular Atrial Fibrillation: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
gastrointestinal (GI) bleed
02/15/2019
Influenza Vaccines and Birth Outcomes
Validations Supported by Traditional Medical Chart Review
cleft lip with cleft palate
cleft lip without cleft palate
cleft palate without cleft lip
02/06/2019
Machine Learning Pilot for Electronic Phenotyping of Health Outcomes of Interest
Novel Approaches to More Efficient Outcome Validation
11/14/2018
13-Valent Pneumococcal Conjugate Vaccination (PCV13) and Kawasaki Disease
Validations Supported by Traditional Medical Chart Review
Kawasaki disease
10/24/2018
Validation of Anaphylaxis Using Machine Learning
Novel Approaches to More Efficient Outcome Validation
anaphylaxis
10/11/2018
Validation of Stillbirth in ICD-10-CM
Validations Supported by Traditional Medical Chart Review
stillbirth
07/17/2018
Gastrointestinal Bleeding Algorithm Defined in "Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Gastrointestinal (GI) Bleeding Following New Use of Warfarin Compared with Statins"
Outcomes Assessed in Inferential Analyses
gastrointestinal (GI) bleed
06/25/2018
Coding Trend Analyses: Rhabdomyolysis
Coding Trend Analyses
rhabdomyolysis
06/15/2018
Coding Trend Analyses: Myocarditis
Coding Trend Analyses
myocarditis
06/15/2018
Coding Trend Analyses: Myositis
Coding Trend Analyses
myositis
06/15/2018
Gastrointestinal Bleed Algorithm Defined in "PROMPT: Rivaroxaban Surveillance, Gastrointestinal Bleed"
Outcomes Assessed in Inferential Analyses
gastrointestinal (GI) bleed
05/10/2018
Intracranial Hemorrhage Algorithm Defined in "PROMPT: Rivaroxaban Surveillance, Intracranial Hemorrhage"
Outcomes Assessed in Inferential Analyses
intracranial hemorrhage
05/07/2018
Intussusception Algorithm Defined in "Intussusception Risk After Rotavirus Vaccination in U.S. Infants (PRISM)"
Outcomes Assessed in Inferential Analyses
intussusception
05/07/2018
Clostridium difficile Algorithm Defined in "Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Clostridium difficile Events After Use of Oral Clindamycin versus Penicillins"
Outcomes Assessed in Inferential Analyses
clostridium difficile
04/30/2018
Complex Regional Pain Syndrome (CRPS), Uveitis, Acute Disseminated Encephalomyelitis (ADEM), and Acute Pericarditis Algorithms Defined in "Sequential Analysis of Gardasil 9 Safety"
Outcomes Assessed in Inferential Analyses
acute disseminated encephalomyelitis (ADEM)
acute pericarditis
complex regional pain syndrome (CRPS)
uveitis
04/30/2018
Hypoglycemia Algorithm Defined in "Testing Routine Querying Tools with Known Positive Exposure-Outcome Associations: Hypoglycemia Events After Use of Glyburide versus Glipizide"
Outcomes Assessed in Inferential Analyses
hypoglycemia
04/26/2018
Seizure Algorithm Defined in "Seizure following Ranolazine Use: A Self-Controlled Risk Interval Analysis"
Outcomes Assessed in Inferential Analyses
seizure
04/24/2018
Venous Thromboembolism Algorithm Defined in "Venous Thromboembolism following Continuous or Extended Cycle Contraceptive Use: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
venous thromboembolism (VTE)
04/23/2018
Stroke Algorithm Defined in "Stroke following Atypical Antipsychotic or Z-Hypnotic Use in Patients with Prior Use of Selective Serotonin Reuptake Inhibitors (SSRIs): A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
hemorrhagic stroke
ischemic stroke
stroke
04/23/2018
Stroke Algorithm Defined in "Stroke following Typical or Atypical Antipsychotic Use in Non-Elderly Patients: A Propensity Score Matched Analysis"
Outcomes Assessed in Inferential Analyses
hemorrhagic stroke
ischemic stroke
stroke
04/23/2018
Sentinel Medical Chart Review Gap Analysis
Novel Approaches to More Efficient Outcome Validation
04/18/2018
Mini-Sentinel: Automated Approaches to Anaphylaxis Case Classification Using Unstructured Data
Novel Approaches to More Efficient Outcome Validation
anaphylaxis
03/07/2018
Validation of Lymphoma in ICD-10-CM
Validations Supported by Traditional Medical Chart Review
lymphoma
02/22/2018
Influenza Vaccines and Pregnancy Outcomes (PRISM)
Validations Supported by Traditional Medical Chart Review
spontaneous abortion (SAB)
01/26/2018
Validation of Serious Infections among an Immunocompromised Population
Validations Supported by Traditional Medical Chart Review
serious infection
11/19/2017
Evaluation of New Technologies Associated with Chart Review
Novel Approaches to More Efficient Outcome Validation
08/16/2017
Thromboembolic Events After Immunoglobulin Administration
Validations Supported by Traditional Medical Chart Review
acute myocardial infarction (AMI)
ischemic stroke
thromboembolic events (TEE)
venous thromboembolism (VTE)
07/13/2017
Parenteral Iron and Anaphylactoid Reactions
Validations Supported by Traditional Medical Chart Review
anaphylactoid reaction
07/22/2016
Health Outcome Algorithm Inventory
Literature Reviews
Achilles tendon rupture (ATR)
Bell’s palsy
Guillain-Barré syndrome
Henoch Schönlein purpura (HSP)
acute intracranial hemorrhage
acute ischemic stroke
acute pancreatitis
acute respiratory failure
acute stroke (ischemic or hemorrhagic)
agranulocytosis
aplastic anemia
asthma exacerbation
attempted suicide
erythema multiforme major
febrile seizure
gastrointestinal (GI) bleed
hip fracture
hypertensive emergency
idiopathic thrombocytopenic purpura
inflammatory bowel disease (IBD)
juvenile rheumatoid arthritis
neutropenia
peripheral neuropathy
premature delivery
pulmonary fibrosis
pulmonary hypertension
rhabdomyolysis
sepsis
severe acute liver injury (SALI)
spontaneous abortion (SAB)
stillbirth
sudden cardiac death
sudden or rapidly-progressing hearing loss
suicide
systemic lupus erythematosus (SLE)
thrombocytopenia
thrombotic thrombocytopenic purpura
toxic epidermal necrolysis
tuberculosis (TB)
type 1 diabetes mellitus
venous thromboembolism (VTE)
05/23/2016
Influenza Vaccines and Febrile Seizures (PRISM)
Validations Supported by Traditional Medical Chart Review
febrile seizure
09/18/2015
Gardasil Vaccination and Venous Thromboembolism (PRISM)
Validations Supported by Traditional Medical Chart Review
venous thromboembolism (VTE)
04/21/2015
16 Health Outcomes of Interest for Surveillance Preparedness
Literature Reviews
Achilles tendon rupture (ATR)
Guillain-Barré syndrome
Henoch Schönlein purpura (HSP)
attempted suicide
erythema multiforme major
febrile seizure
hip fracture
idiopathic thrombocytopenic purpura
peripheral neuropathy
pulmonary hypertension
rhabdomyolysis
severe acute liver injury (SALI)
sudden cardiac death
suicide
thrombocytopenia
toxic epidermal necrolysis
type 1 diabetes mellitus
valvulopathy
ventricular arrhythmia
07/01/2014
Intussusception Risk After Rotavirus Vaccination in U.S. Infants (PRISM)
Validations Supported by Traditional Medical Chart Review
intussusception
02/03/2014
HOI Evidence Reviews (PRISM)
Literature Reviews
Bell’s palsy
Henoch Schönlein purpura (HSP)
Kawasaki disease
acute bronchospasm
acute asthma
acute disseminated encephalomyelitis (ADEM)
bronchospasm
idiopathic facial palsy
intrauterine fetal demise
myocarditis
myopericarditis
optic neuritis
rheumatoid arthritis
spontaneous abortion (SAB)
stillbirth
systemic lupus erythematosus (SLE)
tic
transverse myelitis
uveitis
wheeze
12/25/2013
Validation of Acute Kidney Injury Cases
Validations Supported by Traditional Medical Chart Review
acute kidney injury
12/22/2013
Alternative Methods for Health Outcomes of Interest Validation
Novel Approaches to More Efficient Outcome Validation
09/25/2013
Validation of Anaphylaxis Cases
Validations Supported by Traditional Medical Chart Review
anaphylaxis
03/27/2013
Validation of Severe Liver Injury Cases
Validations Supported by Traditional Medical Chart Review
severe liver injury
01/29/2013
HOI Literature Review - Venous Thromboembolism
Literature Reviews
venous thromboembolism (VTE)
09/04/2011
HOI Literature Review - Gap Analysis
Literature Reviews
Achilles tendon rupture (ATR)
acute respiratory failure
anaphylactic shock
anaphylaxis
angioedema
atrial fibrillation
attempted suicide
cerebrovascular accident (CVA)
congestive heart failure
convulsion
depression
epilepsy
erythema multiforme major
hypersensitivity reaction
infection related to blood products, tissue grafts, or organ transplantation
interstitial lung disease
lymphoma
orthopedic implant removal and revision
pancreatitis
pulmonary fibrosis
seizure
serious cardiac arrhythmia
suicide
toxic epidermal necrolysis
transfusion-related ABO incompatibility reaction
transfusion-related septicemia
transient ischemic attack (TIA)
venous thromboembolism (VTE)
08/18/2011
HOI Literature Review - Hypersensitivity Reactions
Literature Reviews
fever
hypersensitivity reaction
07/29/2011
HOI Literature Review - Orthopedic Implant Removal
Literature Reviews
orthopedic implant removal and revision
07/19/2011
HOI Literature Review - Pulmonary Fibrosis
Literature Reviews
interstitial lung disease
pulmonary fibrosis
07/14/2011
Validation of Acute Myocardial Infarction Cases
Validations Supported by Traditional Medical Chart Review
acute myocardial infarction (AMI)
07/01/2011
HOI Literature Review - Atrial Fibrillation
Literature Reviews
atrial fibrillation
06/30/2011
HOI Literature Review - Erythema Multiforme
Literature Reviews
Stevens–Johnson Syndrome
erythema multiforme major
erythema multiforme minor
toxic epidermal necrolysis
06/16/2011
HOI Literature Review - Transfusion Sepsis
Literature Reviews
transfusion-related sepsis
transfusion-related septicemia
06/15/2011
HOI Literature Review - Respiratory Failure
Literature Reviews
acute respiratory failure
06/13/2011
HOI Literature Review - Anaphylaxis
Literature Reviews
anaphylactic shock
anaphylaxis
angioneurotic edema
06/10/2011
HOI Literature Review - Seizures
Literature Reviews
convulsion
epilepsy
seizure
06/06/2011
HOI Literature Review - CVA/TIA
Literature Reviews
cerebrovascular accident (CVA)
transient ischemic attack (TIA)
06/02/2011
HOI Literature Review - ABO Incompatibility
Literature Reviews
transfusion-related ABO incompatibility reaction
05/27/2011
HOI Literature Review - Lymphomas
Literature Reviews
lymphoma
05/27/2011
HOI Literature Review- Transfusion/Graft Infections
Literature Reviews
infection related to blood product
infection related to tissue graft
tissue graft
05/27/2011
HOI Literature Review - Pancreatitis
Literature Reviews
pancreatitis
05/20/2011
HOI Literature Review - Cardiac Arrhythmias
Literature Reviews
cardiac arrest
including ventricular fibrillation
serious cardiac arrhythmia
sudden cardiac death
supraventricular tachycardia (SVT)
torsades de pointes
03/02/2011
HOI Literature Review - Depression
Literature Reviews
depression
02/08/2011
HOI Literature Review - Congestive Heart Failure
Literature Reviews
congestive heart failure
02/08/2011
HOI Literature Review - Suicide
Literature Reviews
attempted suicide
suicidal ideation
suicide
02/07/2011
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